{"id":"W2168632571","doi":"10.1186/1476-4598-9-216","title":"XIAP gene expression and function is regulated by autocrine and paracrine TGF-β signaling","year":2010,"lang":"en","type":"article","venue":"Molecular Cancer","topic":"Cell death mechanisms and regulation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":35,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université du Québec à Trois-Rivières","funders":"Canadian Institutes of Health Research; Cancer Research Society","keywords":"XIAP; Autocrine signalling; Paracrine signalling; Biology; Cancer research; Cancer cell; Inhibitor of apoptosis; Transforming growth factor beta; Stromal cell; Signal transduction; Cancer; Cell biology; Cell culture; Apoptosis; Programmed cell death; Caspase; Receptor","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00007130942,0.0001426243,0.0001034424,0.00002678293,0.00009068917,0.00003001583,0.00004384627,0.0001546643,0.00009282143],"category_scores_gemma":[0.000007377692,0.0001291504,0.00003326075,0.00004647108,0.0000456689,0.000005827902,0.00007290275,0.00009279009,9.713593e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000005438323,"about_ca_system_score_gemma":0.00001925775,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0000398655,"about_ca_topic_score_gemma":0.000007617887,"domain_scores_codex":[0.9992225,0.00001951022,0.0001266531,0.000365657,0.0001047385,0.000160944],"domain_scores_gemma":[0.9995978,0.000002224322,0.000057941,0.0002018528,0.0000528996,0.00008729706],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00005827365,0.00001384606,0.0001752127,0.00001470975,0.00002341912,0.000002062704,0.00001753214,0.00003449657,0.9894293,0.00003641434,0.001034747,0.009159993],"study_design_scores_gemma":[0.0005344882,0.00008994016,0.0004680124,0.00001272086,0.00003137952,0.00002035178,0.000006260127,0.0005804537,0.9594796,0.0001493227,0.03846063,0.0001668528],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9850565,0.004150684,0.01014982,0.0002227168,0.0001834299,0.0001533629,0.00001497662,0.00001612963,0.00005234321],"genre_scores_gemma":[0.9964824,0.0005732566,0.001298489,0.0003955393,0.0001231364,0.00002948388,0.0001244923,0.00002674253,0.0009464907],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.03742588,"threshold_uncertainty_score":0.52666,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.004218633617227922,"score_gpt":0.2239945229271669,"score_spread":0.2197758893099389,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}