{"id":"W2168634761","doi":"10.1158/0008-5472.can-09-1778","title":"Loss of Collapsin Response Mediator Protein1, as Detected by iTRAQ Analysis, Promotes Invasion of Human Gliomas Expressing Mutant EGFRvIII","year":2009,"lang":"en","type":"article","venue":"Cancer Research","topic":"Axon Guidance and Neuronal Signaling","field":"Neuroscience","cited_by":31,"is_retracted":false,"has_abstract":true,"ca_institutions":"SickKids Foundation; Hospital for Sick Children; Toronto Western Hospital; York University; University of Toronto","funders":"","keywords":"Gene knockdown; Mutant; Western blot; Cancer research; Cell culture; Biology; Phenotype; Molecular biology; Gene; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001693849,0.0001875217,0.0004389079,0.0006929151,0.0004274824,0.00004390332,0.0006367596,0.0001234017,0.00033088],"category_scores_gemma":[0.002081145,0.0001670142,0.0001374162,0.003363393,0.0005400443,0.0001774725,0.0001793667,0.0003805487,0.000009230752],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002185844,"about_ca_system_score_gemma":0.0004270988,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001792985,"about_ca_topic_score_gemma":0.00006047502,"domain_scores_codex":[0.9951547,0.001291325,0.0005827647,0.0006745588,0.001681589,0.0006150363],"domain_scores_gemma":[0.9978635,0.0007675641,0.000288391,0.0005161798,0.0003550894,0.0002093191],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.002346329,0.0001589867,0.0007726211,0.0000600747,0.00002096021,0.00006787619,0.000469555,0.00002258077,0.9954388,0.00003971755,0.0001825561,0.0004199301],"study_design_scores_gemma":[0.0006127073,0.0009367124,0.001674661,0.0002123139,0.00003160123,0.000005763438,0.00005824004,0.00007939633,0.9957727,0.0002527499,0.0002081025,0.0001550223],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9978473,0.0006642517,0.00001574941,0.0004386962,0.00002813653,0.0007835032,0.00006902623,0.00003693835,0.0001163529],"genre_scores_gemma":[0.9993401,0.0001093007,0.00002625834,0.00006208103,0.00004438496,0.00008728654,0.00000365202,0.00002396678,0.0003029288],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002708731,"threshold_uncertainty_score":0.6810642,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.08872576312473403,"score_gpt":0.4045628746448651,"score_spread":0.3158371115201311,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}