{"id":"W2168649860","doi":"10.1038/nature08486","title":"Pten in stromal fibroblasts suppresses mammary epithelial tumours","year":2009,"lang":"en","type":"article","venue":"Nature","topic":"Cell Adhesion Molecules Research","field":"Medicine","cited_by":495,"is_retracted":false,"has_abstract":false,"ca_institutions":"McGill University","funders":"Eunice Kennedy Shriver National Institute of Child Health and Human Development; National Cancer Institute","keywords":"PTEN; Stromal cell; Stroma; Cancer research; Biology; Angiogenesis; Extracellular matrix; Carcinogenesis; Neoplastic transformation; Tumor microenvironment; Pathology; Cell biology; PI3K/AKT/mTOR pathway; Cancer; Signal transduction; Immunology; Immunohistochemistry; Medicine; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004572675,0.0005183317,0.0003615347,0.0009335908,0.0003303857,0.0008095696,0.0004810931,0.0005428595,0.003700197],"category_scores_gemma":[0.0003965365,0.0004100474,0.0003479789,0.0004340637,0.0006816779,0.0003189888,0.0003853405,0.001036182,0.0007661464],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004456479,"about_ca_system_score_gemma":0.0006975257,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002130094,"about_ca_topic_score_gemma":0.002800065,"domain_scores_codex":[0.9992021,0.0001603457,0.00007606197,0.0000869974,0.0002637809,0.0002106055],"domain_scores_gemma":[0.9995323,0.0001327047,0.00008026505,0.00006596173,0.00002662522,0.000162108],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0005035972,0.0001305697,0.0002606291,0.00003671523,0.00001513299,0.00016972,0.00003600149,0.0002550343,0.9959537,0.0006971035,0.000228357,0.00171345],"study_design_scores_gemma":[0.00007375695,0.0005213078,0.001970718,0.000004424471,0.00003472094,0.00039697,0.00008813714,0.001355017,0.990484,0.0001832041,0.004881492,0.000006228886],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9873297,0.00147377,0.002338073,0.0006090914,0.0002063407,0.00005377891,0.0009481419,0.0003845079,0.006656585],"genre_scores_gemma":[0.9921972,0.0005681514,0.000574953,0.00008044709,0.00002623965,0.00003401452,0.000430383,0.00003980312,0.006048848],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003700197,"threshold_uncertainty_score":0.01237839,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.008295320273165133,"score_gpt":0.2966727362657127,"score_spread":0.2883774159925476,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}