{"id":"W2168701747","doi":"10.1021/ja043001q","title":"Ligand-Catalyzed Asymmetric Alkynylboration of Enones:  A New Paradigm for Asymmetric Synthesis Using Organoboranes","year":2005,"lang":"en","type":"article","venue":"Journal of the American Chemical Society","topic":"Organoboron and organosilicon chemistry","field":"Chemistry","cited_by":170,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Waterloo","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Chemistry; Ligand (biochemistry); Catalysis; Reagent; Conjugate; Stoichiometry; Chiral ligand; Enantioselective synthesis; Alkynylation; Combinatorial chemistry; Asymmetric induction; Organic chemistry; Receptor","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003026532,0.0002975358,0.0008025955,0.0000717354,0.0001106782,0.00004822802,0.0008193033,0.0001823012,0.000068769],"category_scores_gemma":[0.001184674,0.0002225422,0.0009897787,0.00159252,0.0003100402,0.0001905903,0.0001101519,0.0004046038,0.000002413351],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004320492,"about_ca_system_score_gemma":0.0004840132,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00006195542,"about_ca_topic_score_gemma":7.980256e-7,"domain_scores_codex":[0.9978205,0.00002293379,0.0009340995,0.0002654875,0.000584879,0.0003720936],"domain_scores_gemma":[0.9965239,0.0006104064,0.001950512,0.0004352981,0.0002440622,0.0002358863],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001111366,0.0002078092,0.001158498,0.0001284518,0.0002691185,5.579694e-7,0.0002019338,0.00004200569,0.9762294,0.000005655112,0.002528749,0.01911665],"study_design_scores_gemma":[0.0009046962,0.00002141234,0.0001409999,0.00009611229,0.000388801,0.00007482216,0.0004034666,0.0004795181,0.9958149,0.00006502394,0.001362981,0.0002473192],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9960977,0.0008804252,0.0007847824,0.001891027,0.0000824768,0.00009955808,0.00003529632,0.00002617407,0.00010257],"genre_scores_gemma":[0.9867177,0.0002504628,0.01141401,0.0002896086,0.001205826,0.000004563784,0.000003557008,0.00005829666,0.0000559469],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01958542,"threshold_uncertainty_score":0.9075009,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01566352357518115,"score_gpt":0.2610637860039501,"score_spread":0.2454002624287689,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}