{"id":"W2168712092","doi":"10.1093/hmg/dds304","title":"Genome-wide meta-analysis of common variant differences between men and women","year":2012,"lang":"en","type":"review","venue":"Human Molecular Genetics","topic":"Demographic Trends and Gender Preferences","field":"Social Sciences","cited_by":45,"is_retracted":false,"has_abstract":true,"ca_institutions":"Ottawa Hospital; University of Toronto; Ontario Institute for Cancer Research","funders":"U.S. National Library of Medicine; National Institute of Diabetes and Digestive and Kidney Diseases; National Human Genome Research Institute; National Institute of Mental Health; National Heart, Lung, and Blood Institute; National Institute on Aging; National Institute on Alcohol Abuse and Alcoholism; Instituto de Salud Carlos III; National Health and Medical Research Council; National Institutes of Health; Novo Nordisk; Centre for Medical Systems Biology; Agence Nationale de la Recherche; Universität Greifswald; Raine Medical Research Foundation; Hjartavernd; Chinese Society of Clinical Oncology; Universiteit Antwerpen; Incyte; Medical Research Council; Tartu Ülikool; Compagnia di San Paolo; Emil Aaltosen Säätiö; GlaxoSmithKline; Signe ja Ane Gyllenbergin Säätiö; Deutsche Forschungsgemeinschaft; Nederlandse Organisatie voor Wetenschappelijk Onderzoek; Ministero della Salute; Canadian Institutes of Health Research; Fonds Wetenschappelijk Onderzoek; National Center for Research Resources; Nierstichting; Fondazione Cariplo; Academy of Finland; Sociedad Española de Neumología y Cirugía Torácica; Radboud Universiteit; Schweizerischer Nationalfonds zur Förderung der Wissenschaftlichen Forschung; Ministerio de Ciencia e Innovación; National Institute on Minority Health and Health Disparities; European Commission; Wellcome Trust; Eesti Teadusfondi; ZonMw; Tampereen Tuberkuloosisäätiö; Kela; European Science Foundation; Scottish Government; Netherlands Heart Institute; Deutsches Zentrum für Herz-Kreislaufforschung; Cancer Research UK; Abbott Laboratories; National Institute for Health and Care Research; Unity through Knowledge Fund; Münchner Zentrum für Gesundheitswissenschaften; Pfizer; Bundesministerium für Bildung und Forschung; Women and Infants Research Foundation; Erasmus Medisch Centrum; Vrije Universiteit Amsterdam; National Science Foundation","keywords":"Minor allele frequency; Genetics; Single-nucleotide polymorphism; Genome-wide association study; Biology; Allele; Allele frequency; Meta-analysis; Genetic association; Sex ratio; Demography; Population; Genotype; Medicine; Gene; Internal medicine","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.001222134,0.0004680209,0.003973141,0.0007161978,0.000336958,0.0001343868,0.0008275682,0.0003934809,0.0006368228],"category_scores_gemma":[0.00001706062,0.0003614167,0.001527397,0.001163978,0.0005350189,0.00003993394,0.0002430996,0.0002593063,0.00000452529],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00004133039,"about_ca_system_score_gemma":0.0001198454,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003917155,"about_ca_topic_score_gemma":0.0006347065,"domain_scores_codex":[0.9960341,0.001266383,0.0008599374,0.0005343301,0.0006992448,0.0006060006],"domain_scores_gemma":[0.9979879,0.0002694059,0.0007051644,0.0006190967,0.00007495679,0.0003434929],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"meta_analysis","study_design_gemma":"meta_analysis","study_design_scores_codex":[0.000001527298,0.0002442022,0.00745985,0.002879932,0.5457437,0.00002716251,0.02820182,0.000003411187,0.000002329153,0.006904502,0.00002536061,0.4085062],"study_design_scores_gemma":[0.00006165041,0.00007135609,0.02503099,0.00004352908,0.5540365,4.819338e-7,0.0006969546,4.954608e-7,2.786736e-7,0.002852742,0.4165979,0.0006071749],"study_design_candidate":"meta_analysis","study_design_consensus":"meta_analysis","genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.002736645,0.9895584,0.0001123922,0.00001610488,0.00003029007,0.0003845988,0.0001868766,0.00002564392,0.006949029],"genre_scores_gemma":[0.136658,0.8625506,0.0001538752,0.00001473866,0.0000646452,0.00008099054,0.0001318268,0.0000290756,0.0003161894],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.4165725,"threshold_uncertainty_score":0.9998838,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.2255915939691615,"score_gpt":0.3813506072306561,"score_spread":0.1557590132614945,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). 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