{"id":"W2168717051","doi":"10.4049/jimmunol.170.7.3603","title":"Role of MHC Class I in Immune Surveillance of Mitochondrial DNA Integrity","year":2003,"lang":"en","type":"article","venue":"The Journal of Immunology","topic":"Mitochondrial Function and Pathology","field":"Biochemistry, Genetics and Molecular Biology","cited_by":26,"is_retracted":false,"has_abstract":true,"ca_institutions":"SickKids Foundation; Hospital for Sick Children; University of Toronto","funders":"Hospital for Sick Children","keywords":"Mitochondrial DNA; Biology; MHC class I; Immune system; DNA; Major histocompatibility complex; MHC class II; Genetics; Computational biology; Immunology; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000143755,0.0001934464,0.00008640501,0.0001525709,0.000190064,0.0003521684,0.0001483279,0.0002249453,0.001596812],"category_scores_gemma":[0.000176309,0.00004976026,0.00008974324,0.00004956462,0.0002308137,0.0002642167,0.0002174042,0.0002856631,0.0003861094],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001893089,"about_ca_system_score_gemma":0.00009995395,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001774733,"about_ca_topic_score_gemma":0.0001573036,"domain_scores_codex":[0.9999325,0.00001506587,0.000003223151,0.00001390431,0.00001073188,0.00002459599],"domain_scores_gemma":[0.9998653,0.00002032593,0.00003782038,0.00001075324,0.00002096777,0.00004485247],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001754885,0.0000260002,0.002740552,0.0000380437,0.000005258566,0.0002912171,0.00003575631,0.00005750073,0.9857638,0.0009035814,0.0001563491,0.009806441],"study_design_scores_gemma":[0.00009802155,0.001300409,0.04863757,0.0001063469,0.00005488033,0.006043854,0.0004290612,0.00279298,0.9168999,0.002567622,0.02104672,0.00002260821],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9785398,0.01070403,0.004923528,0.000600185,0.0001156726,0.0000169019,0.00008088724,0.00004997887,0.004968823],"genre_scores_gemma":[0.996004,0.001741596,0.0009335359,0.00005489356,0.00004562665,0.000005375885,0.00004394866,0.000003975263,0.001166967],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001596812,"threshold_uncertainty_score":0.005341828,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0084225229431432,"score_gpt":0.2323064805562271,"score_spread":0.2238839576130839,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}