{"id":"W2168734275","doi":"10.1128/mcb.22.8.2524-2535.2002","title":"The Direct Recruitment of BLNK to Immunoglobulin α Couples the B-Cell Antigen Receptor to Distal Signaling Pathways","year":2002,"lang":"en","type":"article","venue":"Molecular and Cellular Biology","topic":"Monoclonal and Polyclonal Antibodies Research","field":"Medicine","cited_by":124,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia","funders":"National Institute of Allergy and Infectious Diseases; National Institute of General Medical Sciences; National Heart, Lung, and Blood Institute; National Institutes of Health","keywords":"Syk; Biology; Cell biology; breakpoint cluster region; Phosphorylation; B-cell receptor; Receptor; Signal transduction; Immunoreceptor tyrosine-based activation motif; B cell; Antibody; Signal transducing adaptor protein; Molecular biology; Immunology; Tyrosine kinase; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001186057,0.0003344715,0.0001459403,0.0001441963,0.0001965061,0.0003548942,0.000159586,0.0002185655,0.002217671],"category_scores_gemma":[0.0001526623,0.0001396971,0.0001894067,0.0001075786,0.0002326234,0.0002865843,0.000424534,0.000426139,0.0009636006],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005590991,"about_ca_system_score_gemma":0.0001876394,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002566526,"about_ca_topic_score_gemma":0.0005035191,"domain_scores_codex":[0.9998388,0.00002312964,0.00001169663,0.0000376728,0.00003836304,0.00005024168],"domain_scores_gemma":[0.9999303,0.00001073314,0.00001748701,0.000007796406,0.00000706591,0.00002659216],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00007147602,0.000009680102,0.0001534097,0.00001801465,0.000001283731,0.00003502113,0.000005744264,0.00001728506,0.9990332,0.0001081466,0.00001815774,0.0005285444],"study_design_scores_gemma":[0.00002029165,0.0001060474,0.004046357,0.000005154543,0.000006214922,0.0003791563,0.00001667869,0.0003109321,0.9933868,0.00006700904,0.001653351,0.000002093492],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9942067,0.0009373073,0.002905737,0.00008522214,0.00002056701,0.00001808162,0.0001377379,0.00004268849,0.001645933],"genre_scores_gemma":[0.9917319,0.0008910081,0.00288094,0.0000603391,0.00001497168,0.00001932047,0.0004255731,0.00001146842,0.003964505],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002217671,"threshold_uncertainty_score":0.007418871,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0426630470216853,"score_gpt":0.2823130894927833,"score_spread":0.239650042471098,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}