{"id":"W2168734275","doi":"10.1128/mcb.22.8.2524-2535.2002","title":"The Direct Recruitment of BLNK to Immunoglobulin α Couples the B-Cell Antigen Receptor to Distal Signaling Pathways","year":2002,"lang":"en","type":"article","venue":"Molecular and Cellular Biology","topic":"Monoclonal and Polyclonal Antibodies Research","field":"Medicine","cited_by":124,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia","funders":"National Institute of Allergy and Infectious Diseases; National Institute of General Medical Sciences; National Heart, Lung, and Blood Institute; National Institutes of Health","keywords":"Syk; Biology; Cell biology; breakpoint cluster region; Phosphorylation; B-cell receptor; Receptor; Signal transduction; Immunoreceptor tyrosine-based activation motif; B cell; Antibody; Signal transducing adaptor protein; Molecular biology; Immunology; Tyrosine kinase; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003779689,0.0001522681,0.0002589801,0.00004353772,0.000221863,0.00001969769,0.0001997028,0.00007280381,0.0001176395],"category_scores_gemma":[0.00006439535,0.00007950806,0.0001233959,0.0001645922,0.00018502,0.000006728833,0.0001738867,0.0001447623,0.00007468298],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001693743,"about_ca_system_score_gemma":0.00002082553,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001104649,"about_ca_topic_score_gemma":0.000005839612,"domain_scores_codex":[0.9987859,0.0001592583,0.0002592433,0.0002620786,0.000182738,0.0003508485],"domain_scores_gemma":[0.9992698,0.0001492209,0.00004638946,0.000302486,0.00007428384,0.0001577769],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002005745,0.00008436447,0.001010791,0.00002515415,0.0000802304,0.00002841557,0.0003674985,0.000007378448,0.9821072,0.0008233005,0.00058032,0.01468474],"study_design_scores_gemma":[0.0002962308,0.0008515669,0.0002360991,0.00003012298,0.00002423083,0.00001057472,0.0001832627,0.0001162182,0.7259451,0.00006304377,0.2721329,0.0001106263],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9744563,0.01753456,0.0005890624,0.00407833,0.00008463698,0.0007675028,0.00004399485,0.0000118951,0.002433707],"genre_scores_gemma":[0.9959267,0.001294307,0.0003388132,0.0006238559,0.00007072659,0.00005931461,0.00003714084,0.00001503316,0.001634147],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.2715526,"threshold_uncertainty_score":0.3242244,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0426630470216853,"score_gpt":0.2823130894927833,"score_spread":0.239650042471098,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}