{"id":"W2168750294","doi":"10.3748/wjg.14.6360","title":"Protective effects of anti-ricin A-chain RNA aptamer against ricin toxicity","year":2008,"lang":"en","type":"article","venue":"World Journal of Gastroenterology","topic":"Toxin Mechanisms and Immunotoxins","field":"Immunology and Microbiology","cited_by":24,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University","funders":"National Institute of Environmental Health Sciences; National Institute of Allergy and Infectious Diseases","keywords":"Ricin; Luciferase; Cytotoxicity; Molecular biology; Chinese hamster ovary cell; Aptamer; Chemistry; RNA; Ribosome-inactivating protein; Biochemistry; Transfection; Biology; In vitro; Ribosome; Toxin; Receptor","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001476204,0.0003976497,0.0002277113,0.0001326726,0.00007336635,0.0001411672,0.0001417698,0.0003240757,0.001069002],"category_scores_gemma":[0.0001317744,0.0000586631,0.0001899678,0.00006340975,0.000155798,0.0001476457,0.00009159561,0.0002457497,0.0003156647],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001461023,"about_ca_system_score_gemma":0.0001055609,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001215524,"about_ca_topic_score_gemma":0.0001005972,"domain_scores_codex":[0.9998893,0.00002130034,0.00001014902,0.00002975265,0.00002837897,0.0000211897],"domain_scores_gemma":[0.9999105,0.00002182055,0.00002902912,0.0000107278,0.0000152452,0.00001257905],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00004440116,0.00001486011,0.00004399013,0.00002245158,0.0000022211,0.00001783301,0.00000457718,0.0000809862,0.9990531,0.00001925632,0.00001079753,0.0006854933],"study_design_scores_gemma":[0.000006665887,0.0003234696,0.0005388225,0.000001603876,0.000006367122,0.00009079705,0.000003393367,0.0004914505,0.9980994,0.00000903344,0.0004276145,0.000001379922],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9918427,0.001807224,0.004889828,0.00009235437,0.00002340747,0.00003927378,0.00009398048,0.0001097254,0.001101448],"genre_scores_gemma":[0.9954265,0.00056661,0.002494305,0.00007576444,0.00001367079,0.0000246238,0.0001700881,0.00001040699,0.001218046],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001069002,"threshold_uncertainty_score":0.003576219,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.007393828654054679,"score_gpt":0.2084597703979669,"score_spread":0.2010659417439122,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}