{"id":"W2168831067","doi":"10.1091/mbc.e06-06-0567","title":"Endogenous ARF6 Interacts with Rac1 upon Angiotensin II Stimulation to Regulate Membrane Ruffling and Cell Migration","year":2006,"lang":"en","type":"article","venue":"Molecular Biology of the Cell","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":63,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université de Montréal","funders":"Canadian Institutes of Health Research; McGill University","keywords":"Membrane ruffling; Biology; RAC1; Cell biology; Endogeny; Stimulation; Angiotensin II; Cell migration; Rac GTP-Binding Proteins; Cell membrane; Cell; Signal transduction; Cytoskeleton; Neuroscience; Receptor; Biochemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001521419,0.0001677346,0.0001683574,0.00005165882,0.0001167485,0.00001232015,0.0001402546,0.000159974,0.00000795789],"category_scores_gemma":[0.00001429603,0.0001225317,0.00007848423,0.00008713071,0.00004881313,0.000003324235,0.0001260257,0.00007111521,0.000001405301],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000009659617,"about_ca_system_score_gemma":0.00002453429,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001228539,"about_ca_topic_score_gemma":0.00005180126,"domain_scores_codex":[0.9990796,0.0001009429,0.0002130521,0.0003239852,0.00007874626,0.0002036588],"domain_scores_gemma":[0.9994161,0.00001053499,0.0001492512,0.00029315,0.00008747978,0.00004352249],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001130183,0.0000451574,0.0002685315,0.00001301316,0.00001576891,0.000002363892,0.00006032879,0.009114308,0.9900934,0.00005067896,0.00003089142,0.0001925125],"study_design_scores_gemma":[0.0004679291,0.0005109206,0.0002278389,0.00001998685,0.00003608557,0.00001692437,0.0000145881,0.0004538602,0.9968662,0.0001683832,0.001061511,0.0001557504],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9831056,0.0007185243,0.01530077,0.0002140886,0.0001009373,0.0002848241,0.000007147187,0.000007962196,0.0002601481],"genre_scores_gemma":[0.9938335,0.00001923197,0.005510603,0.0001717118,0.00006275181,0.000005586664,0.00009426858,0.0000227263,0.000279644],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01072788,"threshold_uncertainty_score":0.4996697,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.005500479251623355,"score_gpt":0.197793600763154,"score_spread":0.1922931215115306,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}