{"id":"W2168833215","doi":"10.1091/mbc.e12-03-0179","title":"RTEL1 contributes to DNA replication and repair and telomere maintenance","year":2012,"lang":"en","type":"article","venue":"Molecular Biology of the Cell","topic":"Telomeres, Telomerase, and Senescence","field":"Medicine","cited_by":116,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia; BC Cancer Agency","funders":"Universitair Medisch Centrum Groningen; Terry Fox Foundation; ZonMw; Wellcome Trust","keywords":"Biology; Telomere; Homologous recombination; Telomerase; DNA replication; Replication protein A; Genome instability; DNA repair; Telomere-binding protein; Minichromosome maintenance; Control of chromosome duplication; Genetics; DNA damage; Cell biology; DNA; Gene; DNA-binding protein; Transcription factor","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002807978,0.0001022315,0.0002198249,0.00004890917,0.00004972479,0.000003215246,0.00008295542,0.00009755181,0.000006241141],"category_scores_gemma":[0.0002663042,0.00006811979,0.00005517645,0.0001235763,0.000225566,0.00002129042,0.0001016676,0.00008692835,0.000005126497],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0000158169,"about_ca_system_score_gemma":0.00001772857,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00002957319,"about_ca_topic_score_gemma":0.000002414905,"domain_scores_codex":[0.999243,0.00006768502,0.0001707507,0.0002403207,0.00005233111,0.0002258694],"domain_scores_gemma":[0.9991879,0.00004456133,0.00007419005,0.0005290429,0.00006225919,0.0001020091],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00006556601,0.0000515526,0.1202676,0.00006601499,0.00003008478,0.000001792363,0.0001395975,1.473769e-7,0.87471,0.00148126,0.0008991152,0.002287261],"study_design_scores_gemma":[0.0005356052,0.000128544,0.1847844,0.00005079393,0.00006457383,0.00004477041,0.00009323406,0.00001262911,0.7969384,0.0003961391,0.01685992,0.00009106461],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9896575,0.005725579,0.0005703963,0.003000694,0.00009877556,0.0003436595,0.000007319887,0.00002864746,0.0005674879],"genre_scores_gemma":[0.99645,0.0001443055,0.001215699,0.001730841,0.000026001,0.00001151837,0.000005658409,0.000009633815,0.000406312],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0777717,"threshold_uncertainty_score":0.2777844,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.007795461437189882,"score_gpt":0.2568289391596976,"score_spread":0.2490334777225078,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}