{"id":"W2168834436","doi":"10.1152/ajplung.00170.2009","title":"Modulation of epithelial sodium channel activity by lipopolysaccharide in alveolar type II cells: involvement of purinergic signaling","year":2009,"lang":"en","type":"article","venue":"American Journal of Physiology-Lung Cellular and Molecular Physiology","topic":"Ion Transport and Channel Regulation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":28,"is_retracted":false,"has_abstract":true,"ca_institutions":"Centre Hospitalier de l’Université de Montréal","funders":"Canadian Institutes of Health Research; Canadian Thoracic Society; Cystic Fibrosis Foundation","keywords":"Purinergic receptor; Purinergic signalling; Cell biology; Lipopolysaccharide; Chemistry; Modulation (music); Epithelial sodium channel; Sodium channel; Signal transduction; Sodium; Endocrinology; Biochemistry; Biology; Adenosine; Physics; Receptor","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002308026,0.0002238009,0.0005899792,0.0001524619,0.00004454938,0.000002580503,0.0001871868,0.0001436768,0.000007586688],"category_scores_gemma":[0.00001378844,0.0002089832,0.0001978666,0.0001640453,0.0002695864,0.00001560536,0.00004832576,0.0001728897,1.880682e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001567581,"about_ca_system_score_gemma":0.00007077098,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00005792366,"about_ca_topic_score_gemma":0.000001920601,"domain_scores_codex":[0.9985639,0.0001825379,0.0005388209,0.0003025096,0.0001506821,0.0002615686],"domain_scores_gemma":[0.9987295,0.00001341849,0.0007572203,0.0002166984,0.0002045682,0.0000786509],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0008909294,0.0002865923,0.00006622539,0.00003935607,0.0001075246,0.000002536691,0.0001562436,0.003597692,0.9938229,0.00003758911,0.00002545898,0.000966908],"study_design_scores_gemma":[0.0008372322,0.002739066,0.005762526,0.0000351835,0.00005631761,0.000004292529,0.0001107713,0.0008662394,0.9889387,0.0004220779,0.00004623685,0.0001813251],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9970611,0.000849065,0.001718212,0.0000749254,0.0001448716,0.0001291803,0.00001190632,0.00000309914,0.00000767101],"genre_scores_gemma":[0.9990655,0.0003651088,0.0002255591,0.0001111146,0.000123962,0.000002062065,0.00007984115,0.00001734574,0.000009505815],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.005696301,"threshold_uncertainty_score":0.8522086,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.004409207860740338,"score_gpt":0.2133575484831153,"score_spread":0.2089483406223749,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}