{"id":"W2168916709","doi":"10.1016/j.toxlet.2008.05.006","title":"The Threshold of Toxicological Concern (TTC) in risk assessment","year":2008,"lang":"en","type":"review","venue":"Toxicology Letters","topic":"Effects and risks of endocrine disrupting chemicals","field":"Environmental Science","cited_by":194,"is_retracted":false,"has_abstract":false,"ca_institutions":"Cantox Health Sciences International","funders":"","keywords":"Toxicology; Genotoxicity; Acceptable daily intake; Risk assessment; Toxicity; Threshold limit value; Tolerable daily intake; No-observed-adverse-effect level; Environmental health; Medicine; Biology; Pesticide; Computer science; Internal medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.002134435,0.001423652,0.003127899,0.003473008,0.0005005558,0.001626174,0.00224599,0.003123763,0.002924188],"category_scores_gemma":[0.002311335,0.0004835204,0.0007199785,0.004249259,0.002277324,0.002365676,0.00102758,0.002651364,0.002311977],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001517393,"about_ca_system_score_gemma":0.002026965,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.003832771,"about_ca_topic_score_gemma":0.005376637,"domain_scores_codex":[0.9990929,0.0002271136,0.000103954,0.0001448949,0.0003903877,0.00004066925],"domain_scores_gemma":[0.9981619,0.001218994,0.0002350765,0.00003972291,0.0002961076,0.00004818598],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00005926879,0.00008734418,0.0003853071,0.01470132,0.0001016886,0.0004560494,0.0001471197,0.001522928,0.002840303,0.01731452,0.02623942,0.9361446],"study_design_scores_gemma":[0.00002457977,0.000198957,0.001436904,0.007467033,0.0002074232,0.002955175,0.0003107084,0.0004656664,0.001977603,0.02107453,0.9638225,0.00005893369],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0001900357,0.9953263,0.001181361,0.000660125,0.0002871419,0.00001152403,0.00002720774,0.00001076304,0.002305537],"genre_scores_gemma":[0.00221939,0.9937895,0.001593983,0.0006167016,0.0002524719,0.00002186376,0.00003460007,0.000003313781,0.001468078],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.003832771,"threshold_uncertainty_score":0.01128805,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03467465019189649,"score_gpt":0.4008722991909477,"score_spread":0.3661976489990513,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}