{"id":"W2168919398","doi":"10.1007/s40120-015-0033-1","title":"Delayed-Release Dimethyl Fumarate and Pregnancy: Preclinical Studies and Pregnancy Outcomes from Clinical Trials and Postmarketing Experience","year":2015,"lang":"en","type":"article","venue":"Neurology and Therapy","topic":"Pregnancy and Medication Impact","field":"Medicine","cited_by":99,"is_retracted":false,"has_abstract":true,"ca_institutions":"Montreal Neurological Institute and Hospital; McGill University","funders":"","keywords":"Medicine; Dimethyl fumarate; Pregnancy; Postmarketing surveillance; Clinical trial; Neurology; Reproductive medicine; Pharmacology; Obstetrics; Anesthesia; Internal medicine; Adverse effect; Psychiatry; Multiple sclerosis","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.02939786,0.0005486842,0.0008453332,0.001257157,0.0004503822,0.001082106,0.0006861044,0.0009658465,0.003460204],"category_scores_gemma":[0.02809965,0.0002815005,0.001000674,0.001346265,0.001109019,0.0008927041,0.0007236446,0.001011275,0.0005756256],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001017159,"about_ca_system_score_gemma":0.001147712,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005540087,"about_ca_topic_score_gemma":0.000837688,"domain_scores_codex":[0.989089,0.006076834,0.001234275,0.000509568,0.002850129,0.0002402989],"domain_scores_gemma":[0.9649069,0.01714513,0.01202234,0.001379787,0.003723493,0.000822288],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"observational","study_design_scores_codex":[0.05375032,0.006447808,0.2033874,0.01060105,0.002413187,0.001663342,0.002549127,0.001185751,0.022329,0.002143319,0.00543124,0.6880986],"study_design_scores_gemma":[0.0152436,0.3610192,0.4134994,0.006428427,0.008535546,0.01403043,0.002206459,0.00298238,0.08344597,0.002844819,0.08943895,0.0003248713],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.813188,0.1611968,0.004543401,0.002299188,0.0001787176,0.002481253,0.002827448,0.00007859214,0.01320658],"genre_scores_gemma":[0.9510585,0.04131598,0.002552387,0.001071774,0.0003398885,0.0005250004,0.001890679,0.00002141093,0.001224283],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.02939786,"threshold_uncertainty_score":0.1554726,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.3501967812369235,"score_gpt":0.5069049779139999,"score_spread":0.1567081966770764,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}