{"id":"W2168929214","doi":"10.1016/s1072-7515(02)01808-2","title":"A636P is Associated with Early-Onset Colon Cancer in Ashkenazi Jews","year":2003,"lang":"en","type":"article","venue":"Journal of the American College of Surgeons","topic":"Genetic factors in colorectal cancer","field":"Medicine","cited_by":25,"is_retracted":false,"has_abstract":true,"ca_institutions":"Jewish General Hospital","funders":"","keywords":"Medicine; MSH2; Colorectal cancer; MSH6; MLH1; Lynch syndrome; Cancer; Familial adenomatous polyposis; Population; Internal medicine; Gastroenterology; Oncology; DNA mismatch repair","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002733563,0.000462171,0.0002691264,0.001503982,0.0008129424,0.0003031875,0.0002663138,0.0006208885,0.002704129],"category_scores_gemma":[0.0008481378,0.000284731,0.0002261207,0.0008912354,0.0004621467,0.0001473144,0.0002762967,0.0003584922,0.0003143079],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000209182,"about_ca_system_score_gemma":0.0002440103,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.004947362,"about_ca_topic_score_gemma":0.006160517,"domain_scores_codex":[0.999752,0.00004625484,0.00002377866,0.00005363936,0.00006692112,0.00005729179],"domain_scores_gemma":[0.9993292,0.0001306031,0.0002761977,0.00003346599,0.0000824888,0.0001481934],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.0003385267,0.00007780932,0.9794647,0.00002176084,0.0000434129,0.005782926,0.0002502078,0.00002832898,0.01069366,0.00004016261,0.0001839511,0.003074486],"study_design_scores_gemma":[0.00001887947,0.0001653709,0.9845805,0.00001043604,0.00004392972,0.0139168,0.0001695184,0.0001102023,0.0006254223,0.00002883708,0.0003251649,0.000004948904],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9995002,0.0001062425,0.0000608643,0.00002437831,0.000004190754,0.000003464679,0.00003248047,0.000005619697,0.0002626139],"genre_scores_gemma":[0.9995987,0.0000696541,0.00008995619,0.00002864504,0.00001201675,0.000002791701,0.00006365,0.000002541451,0.0001319825],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.004947362,"threshold_uncertainty_score":0.009837151,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01440118100097891,"score_gpt":0.2697357386310753,"score_spread":0.2553345576300963,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}