{"id":"W2168957799","doi":"10.1242/jcs.00955","title":"Leukocyte-specific protein 1 targets the ERK/MAP kinase scaffold protein KSR and MEK1 and ERK2 to the actin cytoskeleton","year":2004,"lang":"en","type":"article","venue":"Journal of Cell Science","topic":"Cellular Mechanics and Interactions","field":"Biochemistry, Genetics and Molecular Biology","cited_by":42,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto; University Health Network; Hospital for Sick Children","funders":"","keywords":"Scaffold protein; Cell biology; MAPK/ERK pathway; Cytoskeleton; Biology; Actin cytoskeleton; Actin; Protein kinase A; Kinase; Mitogen-activated protein kinase kinase; Mitogen-activated protein kinase; ASK1; MAP kinase kinase kinase; Signal transduction; Biochemistry; Cell","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0008464307,0.0001095298,0.00009601472,0.00005842575,0.0003741639,0.0001617539,0.000383868,0.00004382247,0.00001046334],"category_scores_gemma":[0.00008371852,0.00006154297,0.00004992778,0.0001918225,0.0001678931,0.00002426708,0.0001672948,0.0001721416,0.000004555391],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00003504283,"about_ca_system_score_gemma":0.0001936435,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001877565,"about_ca_topic_score_gemma":0.00002358258,"domain_scores_codex":[0.9990277,0.00003688545,0.0002115031,0.0002168358,0.0002877216,0.0002193835],"domain_scores_gemma":[0.999256,0.000007425956,0.0001827296,0.0002429446,0.0001617303,0.000149215],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00003470579,0.00003457202,0.000001658887,0.000004945205,0.000004233136,0.000005285465,0.0001123709,0.00005583934,0.9974824,0.0004551625,0.0003087292,0.001500161],"study_design_scores_gemma":[0.0002355878,0.000405901,0.00005817884,0.000029529,0.000005386338,0.0000664071,0.0001952153,0.00002691521,0.8632205,0.0002735004,0.1354048,0.00007803117],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9904456,0.001696901,0.002470543,0.004519106,0.0001637193,0.000356902,0.000001557925,0.000002118334,0.0003435393],"genre_scores_gemma":[0.9974744,0.0001763297,0.001377701,0.0002292165,0.0002115519,0.00001005688,5.268076e-7,0.000008327643,0.0005118563],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1350961,"threshold_uncertainty_score":0.2877804,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.007759754559610622,"score_gpt":0.226953378545695,"score_spread":0.2191936239860844,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}