{"id":"W2168969562","doi":"10.3109/1547691x.2012.724730","title":"A novel T<sub>H</sub>17-type cell is rapidly increased in the liver in response to acetaminophen-induced liver injury: T<sub>H</sub>17 cells and the innate immune response","year":2012,"lang":"en","type":"article","venue":"Journal of Immunotoxicology","topic":"Drug-Induced Hepatotoxicity and Protection","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":26,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto","funders":"Canadian Institutes of Health Research; Canada Research Chairs","keywords":"Immune system; Acetaminophen; Liver injury; Acquired immune system; Innate immune system; Immunology; Natural killer T cell; Cytokine; Interleukin 12; Interleukin 21; T cell; Biology; Cytotoxic T cell; Medicine; Pharmacology; In vitro","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001676034,0.0004221421,0.0004413472,0.0004673154,0.0002017876,0.0003700504,0.0001977261,0.0004863694,0.002737437],"category_scores_gemma":[0.0001716372,0.0001684573,0.0003250374,0.0002828352,0.0003295596,0.0003114434,0.0002639508,0.000687196,0.0009444206],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002216472,"about_ca_system_score_gemma":0.00012106,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001169686,"about_ca_topic_score_gemma":0.0001514531,"domain_scores_codex":[0.9998572,0.00001886966,0.00001448929,0.00003562608,0.00003035988,0.00004330233],"domain_scores_gemma":[0.999778,0.0000261481,0.00006336528,0.00002681213,0.00003624255,0.0000694938],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001243555,0.00009825765,0.01140513,0.0002209246,0.00002461194,0.005271203,0.0001021028,0.00003673662,0.973336,0.0002360365,0.0003978801,0.007627629],"study_design_scores_gemma":[0.0002908764,0.003975858,0.2135207,0.00005913143,0.0002829701,0.04018735,0.0008163527,0.001821038,0.7094629,0.0008018467,0.02872935,0.00005159665],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9896501,0.00325956,0.004059865,0.0002599495,0.0001681544,0.0001040006,0.0005093667,0.0001973932,0.001791664],"genre_scores_gemma":[0.9891929,0.001641178,0.004297732,0.0003907575,0.0002765453,0.0001783199,0.0008477798,0.00004739129,0.003127481],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002737437,"threshold_uncertainty_score":0.009157598,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05805227198676585,"score_gpt":0.3417694541452959,"score_spread":0.28371718215853,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}