{"id":"W2169083951","doi":"10.1007/s00125-004-1535-z","title":"Taurine supplement in early life altered islet morphology, decreased insulitis and delayed the onset of diabetes in non-obese diabetic mice","year":2004,"lang":"en","type":"article","venue":"Diabetologia","topic":"Aldose Reductase and Taurine","field":"Biochemistry, Genetics and Molecular Biology","cited_by":86,"is_retracted":false,"has_abstract":false,"ca_institutions":"Western University; St Joseph's Health Care; Lawson Health Research Institute","funders":"Canadian Institutes of Health Research; Parthenon Trust; Stem Cell Network; Canadian Diabetes Association","keywords":"Insulitis; Internal medicine; Endocrinology; NOD mice; Diabetes mellitus; Islet; Nod; Offspring; Type 1 diabetes; Pancreas; Medicine; Taurine; Pancreatic islets; Beta cell; Biology; Pregnancy","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003066974,0.0002256614,0.0003683292,0.0001143509,0.00003811954,0.00001336964,0.0002533962,0.0001604593,0.00001853694],"category_scores_gemma":[0.0002375009,0.0001803883,0.00006144038,0.0002192189,0.0002873975,0.000007464243,0.0002033683,0.0001763614,0.000004617581],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002415223,"about_ca_system_score_gemma":0.00009614666,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0008295599,"about_ca_topic_score_gemma":0.0005438647,"domain_scores_codex":[0.9984632,0.0001261876,0.0004362577,0.0004017448,0.0001041911,0.0004684072],"domain_scores_gemma":[0.9992836,0.00006615929,0.0001203815,0.0003811822,0.00004267001,0.0001059684],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.0001034973,0.0004212403,0.6855937,0.00005905395,0.0001204474,0.00003680457,0.0002118475,0.00008446226,0.3124663,0.00006744748,0.0004092643,0.0004259756],"study_design_scores_gemma":[0.003005891,0.0005333219,0.7321238,0.0000440562,0.0000278132,0.00000786203,0.0001167275,0.00003002039,0.2633104,0.000413826,0.0001561102,0.0002301296],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9972366,0.001293479,0.00001315123,0.0007681943,0.00007136985,0.0004042538,0.0001785515,0.00000677439,0.00002760456],"genre_scores_gemma":[0.9984297,0.0002562919,0.0003055231,0.0004690257,0.0000565347,0.0001047885,0.0003498293,0.00001990355,0.000008450877],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.04915582,"threshold_uncertainty_score":0.735602,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.006051610916413101,"score_gpt":0.2271605426928218,"score_spread":0.2211089317764087,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}