{"id":"W2169140729","doi":"10.1002/pros.10047","title":"Clusterin expression is significantly enhanced in prostate cancer cells following androgen withdrawal therapy","year":2002,"lang":"en","type":"article","venue":"The Prostate","topic":"Clusterin in disease pathology","field":"Medicine","cited_by":211,"is_retracted":false,"has_abstract":true,"ca_institutions":"Vancouver General Hospital; University of British Columbia","funders":"Shionogi","keywords":"Clusterin; Prostate cancer; Medicine; Prostate; Prostatectomy; Testosterone (patch); Androgen deprivation therapy; Androgen; Immunohistochemistry; Cancer; Urology; Downregulation and upregulation; Cancer research; Oncology; Internal medicine; Pathology; Apoptosis; Biology; Hormone","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00008633656,0.0001228133,0.0002093616,0.000254146,0.0002480824,0.0002683779,0.00008942896,0.0001286354,0.00135079],"category_scores_gemma":[0.0001596838,0.00009928708,0.0001249125,0.0002524309,0.0001697861,0.00009919709,0.0001444659,0.0002758177,0.0002507809],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002930265,"about_ca_system_score_gemma":0.0002189449,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0008459658,"about_ca_topic_score_gemma":0.001123186,"domain_scores_codex":[0.9998922,0.00001563037,0.000006373384,0.00001763989,0.00004118619,0.00002696913],"domain_scores_gemma":[0.9998606,0.00002456356,0.00003459497,0.00001150147,0.00002189653,0.00004681856],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0007603457,0.00005355849,0.007490147,0.00003792809,0.00001554418,0.0001656234,0.00005334872,0.00006205421,0.9887019,0.00001982766,0.0001060214,0.002533622],"study_design_scores_gemma":[0.00006458833,0.002844348,0.4278372,0.000008683218,0.000054852,0.002316932,0.000223027,0.0008410608,0.5616811,0.00003858419,0.004076605,0.00001309786],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9982698,0.0006947982,0.0002470081,0.00002404912,0.000004995401,0.00001129173,0.000131315,0.00002139126,0.0005953801],"genre_scores_gemma":[0.998536,0.0002089219,0.0002462793,0.00001426496,0.000004359017,0.00001937272,0.0003404796,0.00000351822,0.0006268197],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00135079,"threshold_uncertainty_score":0.004518867,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02253093446298069,"score_gpt":0.2859836584873445,"score_spread":0.2634527240243638,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}