{"id":"W2169170755","doi":"10.1371/journal.pone.0094939","title":"Transcriptional Profiling of Mycobacterium tuberculosis Replicating Ex vivo in Blood from HIV- and HIV+ Subjects","year":2014,"lang":"en","type":"article","venue":"PLoS ONE","topic":"Tuberculosis Research and Epidemiology","field":"Medicine","cited_by":25,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Fogarty International Center; National Institute of Allergy and Infectious Diseases; Center for AIDS Research, University of Washington; National Institutes of Health; School of Medicine, New York University; York University; Office of Research and Development; U.S. Department of Veterans Affairs","keywords":"Tuberculosis; ESAT-6; Mycobacterium tuberculosis; Bacteremia; Immunology; Transcriptome; Medicine; Immune system; Virology; Biology; Ex vivo; Virulence; Microbiology; In vivo; Pathology; Gene; Gene expression","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001581805,0.0002264957,0.0005979619,0.0003465649,0.0002596361,0.0006913451,0.0001192775,0.0003444055,0.001298367],"category_scores_gemma":[0.0003737976,0.0001954338,0.0002306569,0.0004855567,0.0001899185,0.0001232572,0.0001992316,0.0003576957,0.0004420748],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001216507,"about_ca_system_score_gemma":0.0001066673,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007937064,"about_ca_topic_score_gemma":0.0009507925,"domain_scores_codex":[0.9998246,0.00002974936,0.00000793655,0.00006778027,0.00003474526,0.00003518598],"domain_scores_gemma":[0.9998305,0.00004036106,0.00002798573,0.00001672013,0.00005429605,0.00003004195],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.003766866,0.0002900598,0.136565,0.000268635,0.0001377521,0.0003702093,0.001229848,0.0002531699,0.8420013,0.00009399833,0.0007447608,0.01427846],"study_design_scores_gemma":[0.00004630743,0.001554223,0.9436444,0.0000524781,0.0002223535,0.0008524843,0.001490754,0.001159989,0.04716301,0.000208975,0.003573219,0.00003185007],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9942773,0.001405002,0.0004928184,0.00006155053,0.00002444783,0.00002749811,0.003260537,0.0000147073,0.0004361713],"genre_scores_gemma":[0.9859391,0.001319939,0.001187101,0.0002777344,0.00008786375,0.0001340195,0.00867539,0.00002943906,0.002349341],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001298367,"threshold_uncertainty_score":0.00434345,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04060182805360323,"score_gpt":0.2685505902857,"score_spread":0.2279487622320968,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}