{"id":"W2169208646","doi":"10.1002/dvdy.20168","title":"Histone deacetylase 1 (HDAC‐1) required for the normal formation of craniofacial cartilage and pectoral fins of the zebrafish","year":2004,"lang":"en","type":"article","venue":"Developmental Dynamics","topic":"Histone Deacetylase Inhibitors Research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":80,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Ottawa","funders":"Natural Sciences and Engineering Research Council of Canada; University of Ottawa; Johns Hopkins University","keywords":"Biology; Zebrafish; Histone deacetylase; Cell biology; Mesenchyme; Embryo; Craniofacial; Cartilage; Morpholino; Embryonic stem cell; Anatomy; Histone; Genetics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001869359,0.0001153349,0.0001241196,0.00003260173,0.0001820658,0.000009862954,0.0002094682,0.00009657905,0.000003375483],"category_scores_gemma":[0.0001055579,0.000084585,0.00008672605,0.0001090111,0.0002821051,0.00001237911,0.000165736,0.00007385608,9.026321e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000162571,"about_ca_system_score_gemma":0.0002297646,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00007386756,"about_ca_topic_score_gemma":0.001248198,"domain_scores_codex":[0.9991392,0.00002557424,0.0002856377,0.000155425,0.0002018158,0.0001923237],"domain_scores_gemma":[0.9995383,0.00001875102,0.0001221173,0.000178292,0.000102037,0.00004051797],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002203038,0.00008590708,0.0007803821,0.0001148224,0.00003107875,9.610021e-7,0.0009637272,0.0002231154,0.9952701,0.0004392336,0.000512891,0.001357496],"study_design_scores_gemma":[0.001340555,0.0001440687,0.005691976,0.00002905222,0.0000182709,0.00003308461,0.0004545313,0.0008182604,0.990083,0.00005396376,0.001182985,0.0001502713],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9952586,0.00007826262,0.003507209,0.000210777,0.0001331555,0.0004340493,0.0001896278,0.000004719854,0.0001836142],"genre_scores_gemma":[0.9980897,0.0000248484,0.001365824,0.0000502694,0.00003692589,0.00003326571,0.0001516084,0.00001614024,0.0002314431],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.005187101,"threshold_uncertainty_score":0.3449276,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01007208394663173,"score_gpt":0.2548634461528069,"score_spread":0.2447913622061752,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}