{"id":"W2169210165","doi":"10.1182/blood-2012-09-451872","title":"A randomized phase 3 trial of thalidomide and prednisone as maintenance therapy after ASCT in patients with MM with a quality-of-life assessment: the National Cancer Institute of Canada Clinicals Trials Group Myeloma 10 Trial","year":2013,"lang":"en","type":"article","venue":"Blood","topic":"Multiple Myeloma Research and Treatments","field":"Medicine","cited_by":144,"is_retracted":false,"has_abstract":true,"ca_institutions":"Ontario Institute for Cancer Research; Juravinski Cancer Centre; BC Cancer Agency; Dr. H. Bliss Murphy Cancer Centre; Hôpital de l'Enfant-Jésus; McGill University; Hôpital Maisonneuve-Rosemont; CancerCare Manitoba; Saint John Regional Hospital; London Health Sciences Centre; Queen Elizabeth II Health Sciences Centre","funders":"National Cancer Institute","keywords":"Medicine; Prednisone; Thalidomide; Hazard ratio; Surgery; Multiple myeloma; Internal medicine; Maintenance therapy; Transplantation; Randomized controlled trial; Autologous stem-cell transplantation; Clinical endpoint; Confidence interval; Chemotherapy","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.003306558,0.000210697,0.001795566,0.0001006605,0.00003644719,0.00001513893,0.0001147512,0.00007414498,0.0002430711],"category_scores_gemma":[0.003886143,0.00009865539,0.0001565452,0.0002036697,0.0003791293,0.0001284354,0.00002823732,0.0001543305,3.340596e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00006390342,"about_ca_system_score_gemma":0.002606306,"about_ca_topic_candidate":true,"about_ca_topic_consensus":true,"about_ca_topic_score_codex":0.0957837,"about_ca_topic_score_gemma":0.02797048,"domain_scores_codex":[0.9955528,0.001216042,0.001442568,0.0002820195,0.00124205,0.0002645255],"domain_scores_gemma":[0.9957648,0.002323246,0.0009483562,0.0002525659,0.0005369405,0.0001740961],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.9622773,0.005075852,0.02875595,0.00007294097,0.002018326,0.000006353292,0.0001044005,0.000001685127,0.00008035063,0.00006336575,0.00005604544,0.001487437],"study_design_scores_gemma":[0.9116969,0.00474805,0.08253253,0.0002325344,0.000212963,8.626257e-7,0.00002936927,0.0000213642,0.0003099462,0.00006493952,0.00005700263,0.00009360505],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9897735,0.0002349904,0.00001418359,0.0004333643,0.00008362057,0.008994492,0.0002291709,0.000004332207,0.000232404],"genre_scores_gemma":[0.9967808,0.0001648073,0.0004719679,0.0001234227,0.000115906,0.002175386,0.00004890857,0.00001634627,0.0001024361],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.06781322,"threshold_uncertainty_score":0.9897665,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.06801261865729823,"score_gpt":0.4037691003261362,"score_spread":0.335756481668838,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}