{"id":"W2169268163","doi":"10.1093/molbev/msj019","title":"Complex Histories of Genes Encoding 3-Hydroxy-3-methylglutaryl-CoenzymeA Reductase","year":2005,"lang":"en","type":"article","venue":"Molecular Biology and Evolution","topic":"Plant biochemistry and biosynthesis","field":"Biochemistry, Genetics and Molecular Biology","cited_by":15,"is_retracted":false,"has_abstract":true,"ca_institutions":"Dalhousie University","funders":"","keywords":"Biology; Operon; Gene; Horizontal gene transfer; Genetics; Reductase; Gene cluster; Mevalonate pathway; Genome; Computational biology; Evolutionary biology; Enzyme; Escherichia coli; Biochemistry; Biosynthesis","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001927559,0.0001767177,0.0002738365,0.0005954201,0.000446592,0.0005835081,0.0002462744,0.0003919459,0.001193264],"category_scores_gemma":[0.0007248016,0.0001976709,0.0002096385,0.0004472366,0.0005386042,0.000535023,0.001019814,0.0005369011,0.0003505243],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003841948,"about_ca_system_score_gemma":0.0002309363,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007062542,"about_ca_topic_score_gemma":0.00121458,"domain_scores_codex":[0.9997309,0.00002365207,0.00001680917,0.000103886,0.00006718656,0.00005751338],"domain_scores_gemma":[0.9992945,0.0001661037,0.0001812068,0.0001198938,0.00008990197,0.0001482818],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001937774,0.00003981509,0.07537662,0.00005816323,0.00003876199,0.0007920914,0.0005399416,0.0004973388,0.9095637,0.0008535238,0.00009479925,0.01195153],"study_design_scores_gemma":[0.00002246095,0.000577349,0.7751508,0.00002644528,0.0001211725,0.009585165,0.001184473,0.002198039,0.1973089,0.003476599,0.01025395,0.00009459939],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9961926,0.0004274675,0.001365571,0.00004861902,0.000003806248,0.00001205951,0.0002261349,0.00003485614,0.001688892],"genre_scores_gemma":[0.9975921,0.0001839815,0.0006194071,0.00003639761,0.000004674756,0.00001078931,0.0003926656,0.00001426715,0.001145819],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001193264,"threshold_uncertainty_score":0.003991842,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.009657292824130923,"score_gpt":0.2482909819590799,"score_spread":0.238633689134949,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}