{"id":"W2169295181","doi":"10.1073/pnas.092025499","title":"Isoform-specific interaction of HP1 with human TAF <sub>II</sub> 130","year":2002,"lang":"en","type":"article","venue":"Proceedings of the National Academy of Sciences","topic":"Genomics and Chromatin Dynamics","field":"Biochemistry, Genetics and Molecular Biology","cited_by":66,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"National Institute of Allergy and Infectious Diseases; National Institute of General Medical Sciences; York University; Irma T. Hirschl Trust; Lauri Strauss Leukemia Foundation; National Institutes of Health; National Science Foundation","keywords":"Heterochromatin protein 1; Transcription factor II D; Biology; Transcription factor II A; General transcription factor; RNA polymerase II; TAF2; Chromodomain; Transcription factor II B; Molecular biology; TATA-Box Binding Protein; Cell biology; Chromatin remodeling; Chromatin; Genetics; Promoter; Transcription factor; Heterochromatin; DNA-binding protein; Gene; Helicase; Gene expression; RNA","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002749238,0.00007174275,0.00009118504,0.00006245908,0.0001456356,0.00001033941,0.0003898419,0.00006763973,0.00000765803],"category_scores_gemma":[0.00003671344,0.00004929733,0.00005136741,0.0002020348,0.0004066609,0.00001995521,0.0001121901,0.00007232493,4.836606e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001230223,"about_ca_system_score_gemma":0.000008321702,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000001242461,"about_ca_topic_score_gemma":1.993627e-7,"domain_scores_codex":[0.9991449,0.000002341097,0.0002209405,0.00016623,0.0003710282,0.00009459708],"domain_scores_gemma":[0.9993951,0.000007741258,0.0003743025,0.00001109288,0.0001935405,0.00001822605],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000007992337,0.00004653691,0.0009464484,0.00002236449,0.00001192931,1.692067e-9,0.00006677711,0.0001150612,0.9939249,0.00385395,0.0006595893,0.0003444085],"study_design_scores_gemma":[0.0001445678,0.0001953827,0.008293486,0.00003699151,0.000005745118,0.00000872767,0.0001386,0.0007235347,0.9877058,0.002217987,0.0004637655,0.0000654233],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9948931,0.0001093013,0.00000283164,0.0003333389,0.00001217699,0.00007928137,0.000009011421,0.000002113923,0.004558788],"genre_scores_gemma":[0.9991313,0.0001132385,0.0005376607,0.0000510795,0.00005377852,0.000003664982,6.71491e-7,0.000004064989,0.0001045699],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.007347038,"threshold_uncertainty_score":0.2010287,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02496734013543966,"score_gpt":0.2577434900204368,"score_spread":0.2327761498849971,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}