{"id":"W2169320130","doi":"10.1016/j.intimp.2007.06.006","title":"Structural modification of the highly potent peptide bradykinin B1 receptor antagonist B9958","year":2007,"lang":"en","type":"article","venue":"International Immunopharmacology","topic":"Chemical Synthesis and Analysis","field":"Biochemistry, Genetics and Molecular Biology","cited_by":29,"is_retracted":false,"has_abstract":false,"ca_institutions":"Centre hospitalier universitaire de Québec","funders":"","keywords":"Bradykinin; Antagonist; Bradykinin receptor; Pharmacology; Peptide; Chemistry; B2 receptor; Receptor antagonist; Receptor; Medicine; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001337006,0.0002996846,0.0002416681,0.0001122845,0.0001755531,0.0001924505,0.0004161195,0.0003146032,0.002611767],"category_scores_gemma":[0.0001264652,0.0001660103,0.0001947879,0.00008497279,0.0001674864,0.0001327166,0.000223275,0.0005792442,0.0008804762],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002573831,"about_ca_system_score_gemma":0.0002557829,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005617667,"about_ca_topic_score_gemma":0.000724831,"domain_scores_codex":[0.9999061,0.00001277126,0.00000660962,0.00001403505,0.00002744629,0.00003319834],"domain_scores_gemma":[0.9999615,0.000005311557,0.00001055809,0.000005557091,0.00000424547,0.00001273897],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001961747,0.00006622264,0.00004683255,0.00002269454,0.000006779291,0.0002023623,0.0000107208,0.0002545789,0.9956114,0.0005071294,0.0001127087,0.002962439],"study_design_scores_gemma":[0.0001043455,0.0006060961,0.0007130747,0.00000733369,0.00001762129,0.0005808224,0.00001214472,0.0007258852,0.9902524,0.0001333099,0.006837234,0.000009804029],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9870777,0.0008662139,0.006107685,0.0003338304,0.0001235299,0.00007674452,0.0002533991,0.0001067726,0.005054131],"genre_scores_gemma":[0.9901057,0.0007732087,0.004073335,0.0001431587,0.00002178839,0.00002880014,0.0003958217,0.00003627291,0.004421871],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002611767,"threshold_uncertainty_score":0.008737206,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01135236630955528,"score_gpt":0.2898633430664641,"score_spread":0.2785109767569088,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}