{"id":"W2169402914","doi":"10.1095/biolreprod.105.042739","title":"Mice Null for Frizzled4 (Fzd4−/−) Are Infertile and Exhibit Impaired Corpora Lutea Formation and Function1","year":2005,"lang":"en","type":"article","venue":"Biology of Reproduction","topic":"Wnt/β-catenin signaling in development and cancer","field":"Biochemistry, Genetics and Molecular Biology","cited_by":127,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Eunice Kennedy Shriver National Institute of Child Health and Human Development; National Institutes of Health; Canadian Institutes of Health Research; University of Virginia; Johns Hopkins University","keywords":"Biology; Corpus luteum; Internal medicine; Endocrinology; Frizzled; Ovary; Cell biology; Wnt signaling pathway; Signal transduction","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002502706,0.00009949629,0.0001231771,0.00004439811,0.00007917978,0.000007003424,0.00003910497,0.0001433224,0.000008337887],"category_scores_gemma":[0.00009052808,0.00009328189,0.00003080516,0.00004310779,0.0001043588,0.00001410875,0.00003495167,0.00003577014,0.000001519303],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001307326,"about_ca_system_score_gemma":0.00002421863,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000007433382,"about_ca_topic_score_gemma":0.00001252505,"domain_scores_codex":[0.9992713,0.00002557386,0.0002016094,0.0003497965,0.00003394421,0.000117739],"domain_scores_gemma":[0.9994887,0.0000079297,0.0001848103,0.0001545872,0.0001358937,0.00002804813],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0003105424,0.00003076837,0.01163943,0.00005834175,0.00004258325,5.324678e-8,0.0001011713,0.00001783594,0.9328656,0.00004321869,0.005100112,0.04979036],"study_design_scores_gemma":[0.0007328282,0.0002755553,0.01529037,0.00001597448,0.00002546122,0.00003384643,0.0001103252,0.00007634032,0.8171879,0.0002594145,0.1658267,0.000165334],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9894564,0.005237909,0.004016148,0.0007120491,0.0002505048,0.0002434409,0.00001275819,0.00001658935,0.00005420494],"genre_scores_gemma":[0.9950854,0.0006562076,0.002935064,0.00005936397,0.0004890391,0.00004857402,0.0001898259,0.000009407859,0.0005270835],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1607265,"threshold_uncertainty_score":0.3803925,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01561418631923327,"score_gpt":0.2399020568086988,"score_spread":0.2242878704894656,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}