{"id":"W2169402914","doi":"10.1095/biolreprod.105.042739","title":"Mice Null for Frizzled4 (Fzd4−/−) Are Infertile and Exhibit Impaired Corpora Lutea Formation and Function1","year":2005,"lang":"en","type":"article","venue":"Biology of Reproduction","topic":"Wnt/β-catenin signaling in development and cancer","field":"Biochemistry, Genetics and Molecular Biology","cited_by":127,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Eunice Kennedy Shriver National Institute of Child Health and Human Development; National Institutes of Health; Canadian Institutes of Health Research; University of Virginia; Johns Hopkins University","keywords":"Biology; Corpus luteum; Internal medicine; Endocrinology; Frizzled; Ovary; Cell biology; Wnt signaling pathway; Signal transduction","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003656452,0.002115227,0.0007161679,0.002880144,0.0005571656,0.0006207719,0.0008822208,0.001167305,0.007410291],"category_scores_gemma":[0.0005165319,0.0008035007,0.0006543401,0.0006361212,0.0009924485,0.0003546623,0.0007498054,0.001150171,0.002442234],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004573802,"about_ca_system_score_gemma":0.0002903122,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001253179,"about_ca_topic_score_gemma":0.002098122,"domain_scores_codex":[0.9993396,0.00005295328,0.00006990632,0.0001277211,0.0003202067,0.00008952521],"domain_scores_gemma":[0.9990299,0.0001178378,0.0005280952,0.00005518618,0.00004088023,0.0002281528],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0003101844,0.00005327359,0.0008958569,0.0001209499,0.0000346479,0.0008681295,0.00007022289,0.00008816074,0.9927867,0.0004178335,0.0004416464,0.003912309],"study_design_scores_gemma":[0.0006100342,0.001793074,0.09932668,0.0002033398,0.000562657,0.03451302,0.0003938523,0.002555127,0.8086039,0.001649383,0.04959148,0.0001972738],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9557849,0.01107796,0.01388948,0.0007154071,0.0002523148,0.0001838441,0.01059875,0.002574676,0.004922723],"genre_scores_gemma":[0.937727,0.008176753,0.01134579,0.0005412429,0.00013104,0.0004071404,0.01159095,0.0006414833,0.02943861],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.007410291,"threshold_uncertainty_score":0.02478987,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01561418631923327,"score_gpt":0.2399020568086988,"score_spread":0.2242878704894656,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}