{"id":"W2169483537","doi":"10.1086/651147","title":"Sm‐p80–Based DNA Vaccine Provides Baboons with Levels of Protection against<i>Schistosoma</i><i>mansoni</i>Infection Comparable to Those Achieved by the Irradiated Cercarial Vaccine","year":2010,"lang":"en","type":"article","venue":"The Journal of Infectious Diseases","topic":"Parasites and Host Interactions","field":"Immunology and Microbiology","cited_by":46,"is_retracted":false,"has_abstract":true,"ca_institutions":"Western University","funders":"National Center for Research Resources; National Institute of Allergy and Infectious Diseases; National Institutes of Health","keywords":"Immunogenicity; Biology; DNA vaccination; Immunology; Immune system; Antigen; Virology; Schistosoma mansoni; Baboon; Vaccination; Schistosomiasis; Antibody; Immunization; Helminths","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001845317,0.0005686713,0.0002983439,0.000259451,0.00007746361,0.0002527698,0.0001315798,0.0003578506,0.001820462],"category_scores_gemma":[0.0001324787,0.0001553933,0.0001691798,0.00007744123,0.0002864627,0.0002309766,0.0001473539,0.000525667,0.0004331875],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001515817,"about_ca_system_score_gemma":0.000175693,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003257329,"about_ca_topic_score_gemma":0.000435864,"domain_scores_codex":[0.9998616,0.00002991531,0.000008995337,0.00003140726,0.00002518367,0.00004298874],"domain_scores_gemma":[0.9998772,0.00001713089,0.0000418494,0.000008086366,0.00001238208,0.00004327084],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002205925,0.0001306791,0.0002400682,0.00006774109,0.00001097354,0.00004279085,0.00001413846,0.0001274677,0.995744,0.00006257032,0.00004150617,0.00329752],"study_design_scores_gemma":[0.0001684016,0.01107092,0.005617901,0.00003618108,0.00007345268,0.0005299342,0.0000479119,0.001375713,0.9771149,0.00007868405,0.00387499,0.00001079484],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9942345,0.0007677072,0.002926113,0.00008688894,0.00003495776,0.00004883841,0.0001327181,0.0001236401,0.001644601],"genre_scores_gemma":[0.9943331,0.0007479381,0.002277663,0.00007270103,0.00002704753,0.00003310136,0.0003958223,0.0000172952,0.002095322],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001820462,"threshold_uncertainty_score":0.006090105,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01194866224430205,"score_gpt":0.2565390000081004,"score_spread":0.2445903377637984,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}