{"id":"W2169517017","doi":"10.1126/stke.2002.120.pe8","title":"The SAP Family: A New Class of Adaptor-Like Molecules That Regulates Immune Cell Functions","year":2002,"lang":"en","type":"article","venue":"Science s STKE","topic":"Immune Cell Function and Interaction","field":"Immunology and Microbiology","cited_by":21,"is_retracted":false,"has_abstract":true,"ca_institutions":"Montreal Clinical Research Institute; McGill University; Institute for Research in Immunology and Cancer","funders":"","keywords":"Signal transducing adaptor protein; Immune system; Receptor; Cell biology; SH2 domain; Biology; Homology (biology); Signal transduction; Proto-oncogene tyrosine-protein kinase Src; Protein family; Chemistry; Biochemistry; Genetics; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0003231219,0.0001337389,0.000146937,0.0001310253,0.0008207366,0.00005080591,0.0004328688,0.00009671639,0.0009069419],"category_scores_gemma":[0.00006673874,0.00009278196,0.000110953,0.0004373967,0.0009395274,0.0002749236,0.0001012787,0.0002397409,0.0009529396],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00005172475,"about_ca_system_score_gemma":0.00008690629,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002161671,"about_ca_topic_score_gemma":0.00001296154,"domain_scores_codex":[0.9989179,0.00007481922,0.0002610323,0.0002758031,0.00009842795,0.0003720493],"domain_scores_gemma":[0.9990978,0.0001103795,0.0001706905,0.0004685747,0.0001236412,0.00002888532],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00003929853,0.0000544602,0.00005331066,0.000002357838,0.00001707588,2.309333e-7,0.0002802402,0.00001728775,0.9446164,0.0005129382,0.04875112,0.005655251],"study_design_scores_gemma":[0.0004689475,0.0001988567,0.003567503,0.00001585509,0.00002222222,0.00002024505,0.002462958,0.0001907583,0.5781553,0.0001003554,0.4146519,0.000145081],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.7514156,0.03320346,0.001889454,0.002359839,0.02760668,0.0006957877,0.00001340936,0.0002894258,0.1825263],"genre_scores_gemma":[0.8344914,0.0002896919,0.00003395647,0.0001359161,0.00001974532,0.000005744444,0.00000665887,0.000007641766,0.1650092],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.3664611,"threshold_uncertainty_score":0.9998249,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01890308880801883,"score_gpt":0.2133496703219775,"score_spread":0.1944465815139587,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}