{"id":"W2169642388","doi":"10.1139/o10-005","title":"Effect of simultaneous silencing of HPV-18 E6 and E7 on inducing apoptosis in HeLa cellsThis paper is one of a selection of papers published in this special issue entitled “Second International Symposium on Recent Advances in Basic, Clinical, and Social Medicine” and has undergone the Journal's usual peer review process.","year":2010,"lang":"en","type":"article","venue":"Biochemistry and Cell Biology","topic":"Cervical Cancer and HPV Research","field":"Medicine","cited_by":23,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"China Postdoctoral Science Foundation","keywords":"HeLa; Gene silencing; Apoptosis; Transfection; RNA interference; Small hairpin RNA; In vitro; Molecular biology; Gene; Biology; Cancer research; Carcinogen; Oligonucleotide; Chemistry; RNA; Virology; Biochemistry","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":true,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001610615,0.0003574999,0.0003769863,0.0001939877,0.000180262,0.0002566382,0.0002254821,0.0002990496,0.001082106],"category_scores_gemma":[0.0001517357,0.0001370203,0.0003437439,0.000133498,0.0001496852,0.0002016042,0.0002290605,0.0004660464,0.0003127738],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002024784,"about_ca_system_score_gemma":0.0002594804,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0008008551,"about_ca_topic_score_gemma":0.001205107,"domain_scores_codex":[0.9998204,0.00003030589,0.00002950422,0.00003622521,0.0000464047,0.00003720549],"domain_scores_gemma":[0.9998757,0.00004472504,0.00001891536,0.0000168134,0.0000220509,0.0000217854],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001938867,0.00006661424,0.0001817486,0.00007750333,0.00001141099,0.00004388383,0.00003679164,0.00005868923,0.9972157,0.00007104778,0.00007982634,0.001962746],"study_design_scores_gemma":[0.00001852963,0.0005599942,0.001194415,0.000005665511,0.00002326839,0.00006448032,0.00002432486,0.0005805975,0.9959632,0.00001719838,0.001545299,0.000003104894],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9905635,0.003510179,0.002033192,0.0001370754,0.0001312988,0.00007300432,0.0004641789,0.00009360639,0.002993855],"genre_scores_gemma":[0.9911282,0.002186368,0.003144752,0.0001069341,0.00002056912,0.00008611809,0.0006734793,0.00002351411,0.002630002],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001082106,"threshold_uncertainty_score":0.003619969,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02493438262004129,"score_gpt":0.3532839666740386,"score_spread":0.3283495840539973,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}