{"id":"W2169652125","doi":"10.1128/jvi.00856-06","title":"Revealing Domain Structure through Linker-Scanning Analysis of the Murine Leukemia Virus (MuLV) RNase H and MuLV and Human Immunodeficiency Virus Type 1 Integrase Proteins","year":2006,"lang":"en","type":"article","venue":"Journal of Virology","topic":"HIV Research and Treatment","field":"Immunology and Microbiology","cited_by":24,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université de Montréal","funders":"National Institute of General Medical Sciences; National Institutes of Health","keywords":"Biology; Integrase; Murine leukemia virus; RNase H; Long terminal repeat; Virology; Molecular biology; Reverse transcriptase; C-terminus; RNase P; Stop codon; Gene; Virus; Genetics; RNA; Amino acid; Genome","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001189602,0.0001939604,0.0001292079,0.000212486,0.00008892959,0.0001757526,0.0001449214,0.0001520091,0.0005623512],"category_scores_gemma":[0.0001125035,0.0001033783,0.0001878191,0.0001639155,0.000105866,0.00008245178,0.0001251819,0.0002831106,0.0001887588],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002122833,"about_ca_system_score_gemma":0.0001216146,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002529296,"about_ca_topic_score_gemma":0.0004669418,"domain_scores_codex":[0.9999361,0.000009618412,0.000003975549,0.00001136127,0.00002295962,0.00001603129],"domain_scores_gemma":[0.999899,0.00002283131,0.00004046048,0.000008341033,0.000008041399,0.00002143711],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00003276683,0.00001046927,0.0004519503,0.000009571389,0.000002254228,0.00002468838,0.000009093902,0.00007032261,0.9987324,0.00005615116,0.000007694626,0.0005926832],"study_design_scores_gemma":[0.00001039473,0.0001508733,0.01346097,0.00000412715,0.00001583108,0.000511274,0.00003707155,0.001842337,0.9821005,0.00007200332,0.001790996,0.000003570327],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9968215,0.0001354483,0.002427618,0.00001137693,0.000001743902,0.000009912911,0.0002326635,0.00001975737,0.0003399974],"genre_scores_gemma":[0.9923728,0.0001563404,0.005210773,0.00002718855,0.000001918462,0.00001610658,0.001224589,0.00002034022,0.0009699978],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0005623512,"threshold_uncertainty_score":0.001881242,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01031163289374615,"score_gpt":0.2702496558630522,"score_spread":0.259938022969306,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}