{"id":"W2169688058","doi":"10.1186/1750-1326-8-s1-p67","title":"Insulin resistance and obesity: how do they affect tau pathology?","year":2013,"lang":"en","type":"article","venue":"Molecular Neurodegeneration","topic":"Alzheimer's disease research and treatments","field":"Medicine","cited_by":1,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université Laval","funders":"","keywords":"Hyperphosphorylation; Insulin resistance; Tau protein; Diabetes mellitus; Endocrinology; Internal medicine; Dementia; Hypothermia; Obesity; Disease; Cognitive decline; Pathogenesis; Neuroscience; Medicine; Biology; Alzheimer's disease; Phosphorylation; Cell biology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00007580193,0.0001425871,0.0001585099,0.00007433839,0.0001048781,0.00009952208,0.00004165843,0.00006491804,0.00002179013],"category_scores_gemma":[0.00008876334,0.0001185595,0.00005143277,0.00008733078,0.00004816597,0.0001235341,0.00003644507,0.0001118759,0.00006775936],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002427443,"about_ca_system_score_gemma":0.00004835572,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001638563,"about_ca_topic_score_gemma":0.00001707196,"domain_scores_codex":[0.9989182,0.0001711614,0.00009396902,0.000343951,0.0002512496,0.0002214948],"domain_scores_gemma":[0.9993324,0.00001889754,0.00003685856,0.0003054209,0.000105364,0.0002010811],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.0003333258,0.0008978828,0.05352737,0.000204839,0.001358423,0.003478103,0.0003535394,0.00002261396,0.9203346,0.002217521,0.005475285,0.01179649],"study_design_scores_gemma":[0.00521102,0.001094178,0.5785992,0.0001007196,0.0006091472,0.000209213,0.00004174597,0.001155856,0.4089207,0.003099681,0.0004567842,0.00050169],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9901323,0.005682999,0.000292627,0.002617896,0.00003917131,0.0007197822,0.000007883896,0.00004924886,0.0004581196],"genre_scores_gemma":[0.9982651,0.0002531497,0.0005499639,0.0005010169,0.00005291041,0.0001068129,0.00008331957,0.00002503898,0.000162647],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.5250719,"threshold_uncertainty_score":0.4834718,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01297907086150266,"score_gpt":0.2564289348356264,"score_spread":0.2434498639741237,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}