{"id":"W2169689184","doi":"10.1086/597016","title":"HIV Drug Resistance Tests: An Update on Methods for Calculating Phenotypic Fold Change from a Viral Genotype","year":2009,"lang":"en","type":"letter","venue":"Clinical Infectious Diseases","topic":"HIV/AIDS drug development and treatment","field":"Medicine","cited_by":2,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"GlaxoSmithKline; Pfizer; Bristol-Myers Squibb; Abbott Laboratories","keywords":"Medicine; Genotype; Phenotype; Human immunodeficiency virus (HIV); Drug resistance; Virology; HIV drug resistance; Drug; Immunology; Viral load; Genetics; Biology; Antiretroviral therapy; Pharmacology; Gene","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.02193271,0.003359863,0.003458327,0.006339504,0.0006082124,0.004399039,0.005781027,0.004558355,0.005110055],"category_scores_gemma":[0.07341225,0.001808908,0.001995746,0.004801438,0.003654779,0.006395413,0.002267769,0.01405369,0.009158357],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00171856,"about_ca_system_score_gemma":0.001526333,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001718967,"about_ca_topic_score_gemma":0.002782344,"domain_scores_codex":[0.9817051,0.005530697,0.003205175,0.001997354,0.007301728,0.000259946],"domain_scores_gemma":[0.918501,0.041204,0.005096329,0.003886767,0.02944397,0.001868001],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0002364539,0.00008489098,0.001743725,0.001816277,0.000228301,0.0001494561,0.0001258562,0.000483265,0.001288311,0.005137081,0.5639568,0.4247496],"study_design_scores_gemma":[0.00005396574,0.0001742363,0.001826505,0.001431166,0.0001288876,0.00127139,0.00004629327,0.001634365,0.001289735,0.005742783,0.9862583,0.0001423944],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","genre_codex":"review","genre_gemma":"commentary","genre_scores_codex":[0.0012398,0.4268876,0.1808815,0.1396435,0.2365646,0.0002367838,0.003126928,0.004433477,0.006985785],"genre_scores_gemma":[0.0109131,0.3195726,0.1938023,0.1375818,0.3111751,0.001132128,0.0032636,0.003852052,0.01870729],"genre_candidate":"commentary","genre_consensus":null,"teacher_disagreement_score":0.02193271,"threshold_uncertainty_score":0.1159926,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.07231684703143507,"score_gpt":0.4215815158006387,"score_spread":0.3492646687692036,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}