{"id":"W2169708176","doi":"10.1139/v07-141","title":"Semi-synthesis and proteasome inhibition of <scp>D</scp>-ring deoxy analogs of (–)-epigallocatechin gallate (EGCG), the active ingredient of green tea extract","year":2008,"lang":"en","type":"article","venue":"Canadian Journal of Chemistry","topic":"Tea Polyphenols and Effects","field":"Medicine","cited_by":12,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"","keywords":"Chemistry; Gallate; Epigallocatechin gallate; Proteasome; Natural product; Green tea; Proteasome inhibitor; Catechin; Green tea extract; Ring (chemistry); Ingredient; Stereochemistry; Polyphenol; Biochemistry; Food science; Organic chemistry; Antioxidant; Nuclear chemistry","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":true,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001108065,0.0004390903,0.000203872,0.0001885932,0.0001491882,0.0001379041,0.0002268337,0.0001614252,0.001228187],"category_scores_gemma":[0.00008008228,0.0001013843,0.0003386656,0.0001271314,0.000129901,0.000176544,0.0001960366,0.0004001021,0.0004377953],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001825174,"about_ca_system_score_gemma":0.0002801904,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003977011,"about_ca_topic_score_gemma":0.0006660072,"domain_scores_codex":[0.9999298,0.00001316035,0.00000998774,0.00001534554,0.00001214124,0.00001957999],"domain_scores_gemma":[0.9999267,0.000009467343,0.00001956453,0.00001555299,0.00001049428,0.00001819096],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002001436,0.00005048179,0.00004337131,0.00006212672,0.000008039316,0.00005367469,0.000008183886,0.00009790323,0.9966737,0.0001181274,0.00005383998,0.00263035],"study_design_scores_gemma":[0.00002652074,0.000563931,0.0004711957,0.00000359943,0.00001545817,0.0001135048,0.000004634732,0.000126046,0.9964641,0.00003443575,0.002173108,0.000003458984],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9676561,0.00766298,0.01513337,0.0001967969,0.0001603993,0.0002601324,0.00169846,0.0002313154,0.007000311],"genre_scores_gemma":[0.9855956,0.002503175,0.007116242,0.00008491454,0.00003061162,0.00008491211,0.00140104,0.00003232208,0.003151114],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001228187,"threshold_uncertainty_score":0.004108667,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01308086709501635,"score_gpt":0.2091712216139798,"score_spread":0.1960903545189635,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}