{"id":"W2169734442","doi":"10.1530/erc-11-0326","title":"Oncostatin M suppresses oestrogen receptor-α expression and is associated with poor outcome in human breast cancer","year":2012,"lang":"en","type":"article","venue":"Endocrine Related Cancer","topic":"Cytokine Signaling Pathways and Interactions","field":"Medicine","cited_by":74,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia; University of Manitoba; University of Victoria; BC Cancer Agency","funders":"BC Cancer Agency; Office of Defense Programs; BC Cancer Foundation; U.S. Department of Defense","keywords":"Oncostatin M; Breast cancer; Cancer research; Signal transduction; Cancer; Estrogen receptor; Internal medicine; Receptor; Cytokine; Biology; Medicine; Endocrinology; Interleukin 6; Cell biology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001425868,0.0001166611,0.0002261604,0.0002128975,0.0000839135,0.0001936429,0.00007956163,0.00008680704,0.0006178475],"category_scores_gemma":[0.000280043,0.00004887358,0.0001645702,0.0003277774,0.0001197943,0.00005920521,0.0001676694,0.0001633556,0.0001376533],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001494238,"about_ca_system_score_gemma":0.0001543625,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005568654,"about_ca_topic_score_gemma":0.0008040817,"domain_scores_codex":[0.99993,0.0000127702,0.000009059525,0.000008610496,0.00001912035,0.00002050755],"domain_scores_gemma":[0.9998661,0.00002150553,0.00005581186,0.00001459069,0.00001133328,0.00003063655],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.006383147,0.0004610187,0.2280527,0.0003150702,0.0002457511,0.00121385,0.0001412471,0.0004686489,0.7083427,0.0001452252,0.001754827,0.05247592],"study_design_scores_gemma":[0.0001348814,0.003596381,0.8823168,0.00001871694,0.0001736345,0.003579223,0.0001992923,0.0008440843,0.1022134,0.0001021103,0.006811597,0.000009783223],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9986269,0.0006182873,0.0001039222,0.00002825872,0.00000826371,0.000007031985,0.0002448553,0.00001491384,0.0003476639],"genre_scores_gemma":[0.9978198,0.0005974924,0.0001273189,0.00002878345,0.000008703996,0.000008814342,0.00101223,0.000003434809,0.0003934735],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0006178475,"threshold_uncertainty_score":0.00206697,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02393066118516944,"score_gpt":0.3328023836853466,"score_spread":0.3088717225001772,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}