{"id":"W2169777993","doi":"10.1139/y11-055","title":"Physiology and pathophysiology of nitrosative and oxidative stress in osteoarthritic joint destruction","year":2011,"lang":"en","type":"review","venue":"Canadian Journal of Physiology and Pharmacology","topic":"Osteoarthritis Treatment and Mechanisms","field":"Medicine","cited_by":48,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Deutsche Sporthochschule Köln","keywords":"Oxidative stress; Pathophysiology; Medicine; Inflammation; Senescence; Reactive oxygen species; Osteoarthritis; Paracrine signalling; Cartilage; Pathogenesis; Cell biology; Immunology; Pathology; Biology; Internal medicine; Anatomy","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":true,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004140711,0.001020851,0.001550369,0.002311317,0.0004463981,0.0008143546,0.0008182633,0.001209282,0.001842074],"category_scores_gemma":[0.000351578,0.0002679287,0.0003865477,0.00217091,0.0006840657,0.001016665,0.000579985,0.001346142,0.001641097],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0007737472,"about_ca_system_score_gemma":0.001328108,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002378932,"about_ca_topic_score_gemma":0.003735697,"domain_scores_codex":[0.9998295,0.00002812515,0.00003032753,0.00002275412,0.0000726544,0.00001661471],"domain_scores_gemma":[0.9998406,0.00004368254,0.00003133178,0.00000481572,0.00005879508,0.00002069609],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001138637,0.0001516755,0.0004241287,0.0244607,0.0001045339,0.0007440721,0.0001954433,0.0005091855,0.009543844,0.004302676,0.02236522,0.9370847],"study_design_scores_gemma":[0.00003130347,0.0001749739,0.004468348,0.004569818,0.0001435518,0.004914894,0.0002080409,0.0001612333,0.002275654,0.004838807,0.9781696,0.00004380213],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0001432806,0.9989236,0.0001269166,0.0001450496,0.0001201089,0.000004784212,0.000007224,0.000004624379,0.0005243804],"genre_scores_gemma":[0.0009609951,0.9981402,0.0002013489,0.00007430673,0.0001171608,0.000005962085,0.00001300632,6.795314e-7,0.000486376],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.002378932,"threshold_uncertainty_score":0.006162405,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03289951019186452,"score_gpt":0.2980800952867841,"score_spread":0.2651805850949195,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}