{"id":"W2169784899","doi":"10.1161/circresaha.107.155531","title":"Transient Receptor Potential Channel 6–Mediated, Localized Cytosolic [Na + ] Transients Drive Na + /Ca 2+ Exchanger–Mediated Ca 2+ Entry in Purinergically Stimulated Aorta Smooth Muscle Cells","year":2007,"lang":"en","type":"article","venue":"Circulation Research","topic":"Ion Channels and Receptors","field":"Neuroscience","cited_by":132,"is_retracted":false,"has_abstract":true,"ca_institutions":"Child and Family Research Institute; Simon Fraser University; University of Calgary","funders":"","keywords":"Cytosol; Sodium-calcium exchanger; Biophysics; Chemistry; Membrane potential; Ion transporter; Intracellular; Vascular smooth muscle; Internal medicine; Endocrinology; Biochemistry; Biology; Membrane","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000232903,0.0003114396,0.0004692893,0.000124481,0.0001782324,0.000433561,0.0004088842,0.0003370195,0.001311911],"category_scores_gemma":[0.0001547667,0.0001883244,0.0004857553,0.0001614777,0.0003413388,0.0004534947,0.0002382065,0.0008735249,0.0006353765],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003425824,"about_ca_system_score_gemma":0.0002470434,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004675023,"about_ca_topic_score_gemma":0.000782901,"domain_scores_codex":[0.99981,0.00002036451,0.00001685131,0.0000391325,0.00005869546,0.00005506561],"domain_scores_gemma":[0.9998375,0.00002370436,0.00004580663,0.00002096568,0.00002060314,0.00005144734],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00004579056,0.000008066013,0.00003835059,0.00001261564,0.000001527986,0.00002157816,0.000005418825,0.00001765799,0.9996346,0.0000329547,0.000008775654,0.0001726849],"study_design_scores_gemma":[0.00002882267,0.0002446786,0.004346141,0.000004039519,0.00001389266,0.0001914143,0.00002610809,0.001484825,0.9927018,0.00003733677,0.0009159856,0.000004934495],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9924446,0.001276574,0.003888255,0.0001732206,0.00005935896,0.00002774981,0.0003187546,0.0001484276,0.001663025],"genre_scores_gemma":[0.9910978,0.001135541,0.003623605,0.0001061082,0.00004367866,0.00003557177,0.000561817,0.00002522833,0.003370704],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001311911,"threshold_uncertainty_score":0.00438875,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03932319292964295,"score_gpt":0.3018586961501351,"score_spread":0.2625355032204921,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}