{"id":"W2169908590","doi":"10.1128/iai.69.11.6942-6950.2001","title":"Dual Role of Lipopolysaccharide (LPS)-Binding Protein in Neutralization of LPS and Enhancement of LPS-Induced Activation of Mononuclear Cells","year":2001,"lang":"en","type":"article","venue":"Infection and Immunity","topic":"Immune Response and Inflammation","field":"Immunology and Microbiology","cited_by":239,"is_retracted":false,"has_abstract":true,"ca_institutions":"Institute for Biological Sciences","funders":"Bundesministerium für Bildung und Forschung; Deutsche Forschungsgemeinschaft","keywords":"Lipopolysaccharide; Lipopolysaccharide binding protein; Tumor necrosis factor alpha; Stimulation; Peripheral blood mononuclear cell; Acute-phase protein; Membrane; Lipid A; CD14; Biology; Bacterial outer membrane; Chemistry; Cell biology; Inflammation; Biochemistry; Immunology; In vitro; Receptor; Endocrinology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003987304,0.0000919159,0.0002477921,0.0002726116,0.00005847651,0.000003392264,0.00003596399,0.000156913,0.00007710212],"category_scores_gemma":[0.00006984956,0.00009345044,0.0000351115,0.0001782117,0.00008988847,0.0002233763,0.00004051189,0.0001350644,0.000001852491],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002321075,"about_ca_system_score_gemma":0.00003063873,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002686768,"about_ca_topic_score_gemma":0.00004237319,"domain_scores_codex":[0.9990106,0.0002664959,0.0004926445,0.00009265065,0.0000355056,0.000102151],"domain_scores_gemma":[0.9992662,0.00005632462,0.0004301562,0.0001316175,0.0001081418,0.000007541745],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0004695014,0.0001918965,0.004009833,0.00008122678,0.00004220588,6.106042e-8,0.001395861,0.00001192711,0.9842561,0.0003245885,0.000001620649,0.00921511],"study_design_scores_gemma":[0.0008720008,0.000445297,0.03049497,0.0001508767,0.00001586899,0.000003761066,0.0005602608,0.00003718063,0.9671767,0.00007752349,0.00009703577,0.00006852766],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9991953,0.0001166364,0.0001177515,0.00001560336,0.0000661214,0.0002935061,0.000002428441,0.000007856705,0.0001848411],"genre_scores_gemma":[0.9994709,0.0003970363,0.00001887658,0.00000260928,0.000003932158,0.000008547241,0.00002145282,0.000006108082,0.00007048347],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.02648513,"threshold_uncertainty_score":0.4061608,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01171956226439355,"score_gpt":0.2327624647379249,"score_spread":0.2210429024735313,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}