{"id":"W2169949084","doi":"10.1128/jvi.76.22.11688-11703.2002","title":"Age-Dependent Resistance to Lethal Alphavirus Encephalitis in Mice: Analysis of Gene Expression in the Central Nervous System and Identification of a Novel Interferon-Inducible Protective Gene, Mouse<i>ISG12</i>","year":2002,"lang":"en","type":"article","venue":"Journal of Virology","topic":"interferon and immune responses","field":"Immunology and Microbiology","cited_by":126,"is_retracted":false,"has_abstract":true,"ca_institutions":"Columbia College","funders":"National Institute of Allergy and Infectious Diseases; National Institutes of Health","keywords":"Biology; Sindbis virus; Alphavirus infection; Alphavirus; Virology; ISG15; Interferon; Gene expression; Immunology; Virus; Encephalitis; Gene; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0009959859,0.0001402785,0.0006088805,0.0007388746,0.00004145573,0.00001007931,0.0003596771,0.0002092457,0.00003276828],"category_scores_gemma":[0.0001364858,0.0001050604,0.0001292288,0.0003845169,0.0001580412,0.00009787508,0.00005610672,0.0003696469,0.000002791008],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001059615,"about_ca_system_score_gemma":0.00002792589,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002160645,"about_ca_topic_score_gemma":0.0003985973,"domain_scores_codex":[0.9974885,0.0008710095,0.001073242,0.0002160745,0.00008650419,0.0002646441],"domain_scores_gemma":[0.9987165,0.0001806489,0.0007305478,0.0002363277,0.0001150477,0.00002088721],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.002161749,0.0003595795,0.0009194814,0.00002945869,0.0002554562,0.00004428282,0.005371477,0.000265977,0.9901756,0.00004997514,0.00005998382,0.0003069646],"study_design_scores_gemma":[0.001418847,0.0006643377,0.06028935,0.00009516005,0.0001543221,0.0002791381,0.002101823,0.00004313338,0.9347917,0.000005094287,0.0000678749,0.00008919813],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.993969,0.003012595,0.002247228,0.0002026129,0.000196403,0.0002758546,0.00004884505,0.000003272116,0.00004424195],"genre_scores_gemma":[0.9994012,0.0001194963,0.0001719066,0.00005546198,0.0000138615,0.00001826049,0.000003955236,0.000008409945,0.0002074949],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.05936987,"threshold_uncertainty_score":0.4284237,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02025910398502223,"score_gpt":0.2566053719865372,"score_spread":0.2363462680015149,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}