{"id":"W2169972145","doi":"10.1128/jvi.75.20.9872-9884.2001","title":"RNA Polymerase II Holoenzyme Modifications Accompany Transcription Reprogramming in Herpes Simplex Virus Type 1-Infected Cells","year":2001,"lang":"en","type":"article","venue":"Journal of Virology","topic":"Herpesvirus Infections and Treatments","field":"Medicine","cited_by":58,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Alberta","funders":"Canadian Institutes of Health Research; Fondation pour la Recherche Médicale","keywords":"Biology; RNA polymerase II; Transcription (linguistics); Transcription factor II D; RNA polymerase II holoenzyme; Cell biology; Transcription preinitiation complex; RNA polymerase; Protein subunit; Viral replication; Transcription factor II E; Herpes simplex virus; Molecular biology; Promoter; Gene expression; Virology; Gene; Virus; Genetics; RNA","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00007324527,0.000196803,0.0002231305,0.0001289536,0.0001189245,0.0004508286,0.0001528642,0.0001286928,0.001173688],"category_scores_gemma":[0.0001193169,0.0001610329,0.0001737654,0.0001410742,0.0001298468,0.0001760787,0.0001473539,0.0004290066,0.0005167355],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003362635,"about_ca_system_score_gemma":0.0001454248,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000603809,"about_ca_topic_score_gemma":0.0006771901,"domain_scores_codex":[0.9998997,0.000006624831,0.000008926774,0.00003863336,0.00002981261,0.0000162343],"domain_scores_gemma":[0.9999263,0.00001227509,0.00001740274,0.0000161841,0.00001047765,0.00001728384],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00003928501,0.000003820538,0.0002414706,0.00001321055,0.000002219835,0.00002666813,0.0000136112,0.00002230149,0.9986041,0.00005015768,0.00001675088,0.000966437],"study_design_scores_gemma":[0.000005530749,0.00004921151,0.009609035,0.000003511751,0.000008801941,0.000166832,0.00003204025,0.0004584994,0.9867628,0.00008211916,0.00281735,0.000004174756],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9880068,0.002343203,0.005902719,0.0000524843,0.00006514196,0.00003218002,0.0008919012,0.0001323485,0.002573199],"genre_scores_gemma":[0.9922503,0.0008860274,0.001992515,0.00003663239,0.00001615407,0.00004431405,0.00104529,0.00004268754,0.003686013],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001173688,"threshold_uncertainty_score":0.003926337,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03500013840202076,"score_gpt":0.3174042625690772,"score_spread":0.2824041241670565,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}