{"id":"W2170077130","doi":"10.1002/anie.201309987","title":"Substrate‐Directed Hydroacylation: Rhodium‐Catalyzed Coupling of Vinylphenols and Nonchelating Aldehydes","year":2014,"lang":"en","type":"article","venue":"Angewandte Chemie International Edition","topic":"Catalytic C–H Functionalization Methods","field":"Chemistry","cited_by":82,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto","funders":"National Institute of General Medical Sciences; Natural Sciences and Engineering Research Council of Canada; Deutscher Akademischer Austauschdienst; Eli Lilly and Company","keywords":"Hydroacylation; Decarbonylation; Aryl; Alkene; Chemistry; Regioselectivity; Aldehyde; Reactivity (psychology); Rhodium; Ligand (biochemistry); Catalysis; Organic chemistry; Alkyl; Combinatorial chemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001949815,0.0005221196,0.0001767467,0.0001298836,0.0001228717,0.0001563002,0.0003836444,0.0002328067,0.001139389],"category_scores_gemma":[0.0001248866,0.0001624761,0.0002139155,0.0001124208,0.0002467927,0.0003144865,0.0003979825,0.0005500491,0.0006312017],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001852233,"about_ca_system_score_gemma":0.0002274958,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004568277,"about_ca_topic_score_gemma":0.000720161,"domain_scores_codex":[0.9998555,0.00002285676,0.00001167975,0.00003611076,0.00002983083,0.00004398879],"domain_scores_gemma":[0.9999284,0.00001124043,0.00001784469,0.00001725569,0.00001274353,0.00001252003],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00004855502,0.00001536621,0.00008089198,0.00008222919,0.000009164544,0.0001912469,0.00005878824,0.0002301214,0.992853,0.0005896393,0.00009383446,0.005747293],"study_design_scores_gemma":[0.000006204951,0.00006600883,0.0001767639,0.000002630082,0.000005505593,0.0001365746,0.000009386278,0.0001997698,0.9965403,0.00005113094,0.002800481,0.000005279273],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9156771,0.003271076,0.06985646,0.0003399055,0.0001406582,0.0001499789,0.0003154105,0.0003343141,0.009915078],"genre_scores_gemma":[0.9818181,0.002065383,0.01152715,0.00007739314,0.00002047642,0.000043781,0.0002344117,0.00004955258,0.00416374],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001139389,"threshold_uncertainty_score":0.003811657,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02028832225817438,"score_gpt":0.2739767123680109,"score_spread":0.2536883901098365,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}