{"id":"W2170084392","doi":"10.1242/dmm.008557","title":"Interleukin-1 receptor antagonist is beneficial after subarachnoid haemorrhage in rat by blocking haem-driven inflammatory pathology","year":2012,"lang":"en","type":"article","venue":"Disease Models & Mechanisms","topic":"Intracerebral and Subarachnoid Hemorrhage Research","field":"Medicine","cited_by":113,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Canadian Institutes of Health Research; Wellcome Trust","keywords":"Inflammation; Receptor antagonist; Interleukin 1 receptor antagonist; Pharmacology; Receptor; Microglia; Cytokine; Blood–brain barrier; Biology; Pathology; Medicine; Immunology; Antagonist; Internal medicine; Central nervous system","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0005923885,0.0005465468,0.0007099783,0.0004086747,0.0002055562,0.00007689149,0.0003381759,0.0003823392,0.00123241],"category_scores_gemma":[0.00008741212,0.0005090897,0.0003079899,0.0003271079,0.0001570398,0.0006204487,0.0002993672,0.0008558595,0.0003979096],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003758403,"about_ca_system_score_gemma":0.0002452611,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00004332566,"about_ca_topic_score_gemma":0.00001764135,"domain_scores_codex":[0.9959963,0.0001901429,0.000703497,0.0007777959,0.0008381977,0.001494075],"domain_scores_gemma":[0.9978546,0.00005249475,0.0001320826,0.0007458081,0.0001745784,0.001040459],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"simulation_or_modeling","study_design_scores_codex":[0.02327349,0.009114349,0.08256045,0.00521638,0.0003298288,0.01583869,0.02189479,0.000445925,0.678013,0.03691022,0.00849847,0.1179045],"study_design_scores_gemma":[0.01069575,0.001022125,0.003166691,0.000778051,0.0008698404,0.0005491145,0.002826729,0.6170217,0.3397043,0.01825822,0.001442615,0.003664898],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9842188,0.00219071,0.009783751,0.001417779,0.0005807571,0.001042395,0.0002992765,0.0001800255,0.0002865393],"genre_scores_gemma":[0.9920191,0.0000722839,0.003751078,0.001838176,0.0004730101,0.0004233461,0.0003154603,0.0001274672,0.0009800444],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.6165757,"threshold_uncertainty_score":0.9997361,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01516666851162954,"score_gpt":0.259220400133516,"score_spread":0.2440537316218865,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}