{"id":"W2170199836","doi":"10.1212/wnl.0000000000001726","title":"Clinical and radiologic reversal of stroke-like episodes in MELAS with high-dose <scp>l</scp> -arginine","year":2015,"lang":"en","type":"article","venue":"Neurology","topic":"Mitochondrial Function and Pathology","field":"Biochemistry, Genetics and Molecular Biology","cited_by":19,"is_retracted":false,"has_abstract":true,"ca_institutions":"Hospital for Sick Children","funders":"United Mitochondrial Disease Foundation","keywords":"Mitochondrial encephalomyopathy; Lactic acidosis; Angiopathy; MELAS syndrome; Medicine; Stroke (engine); Pathophysiology; Cardiology; Perfusion; Internal medicine; Pathology; Mitochondrial myopathy; Endocrinology; Mitochondrial DNA; Biology; Diabetes mellitus","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00033328,0.0006842372,0.0005558753,0.0007288922,0.0003536218,0.0003757632,0.0006274804,0.001349864,0.001821634],"category_scores_gemma":[0.002386479,0.0002167948,0.0003566796,0.0003491106,0.0005993359,0.0004651787,0.0002449508,0.001442742,0.0008076052],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005020705,"about_ca_system_score_gemma":0.0006835952,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.003215575,"about_ca_topic_score_gemma":0.003275388,"domain_scores_codex":[0.9998199,0.00004161593,0.00003131035,0.00002934387,0.00003726801,0.00004043607],"domain_scores_gemma":[0.9992974,0.0001319041,0.0001193602,0.00005886084,0.0001355837,0.0002569245],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"case_report","study_design_gemma":"case_report","study_design_scores_codex":[0.009226155,0.001900422,0.1571991,0.0003147727,0.0002524347,0.738289,0.0004436066,0.000835919,0.03339415,0.0008272635,0.004858049,0.05245905],"study_design_scores_gemma":[0.001103681,0.006574419,0.3253421,0.0001150845,0.0001625811,0.6487937,0.0002024444,0.002176341,0.008774879,0.0006207334,0.00605378,0.00008025357],"study_design_candidate":"case_report","study_design_consensus":"case_report","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9527243,0.003384922,0.003089853,0.003017929,0.0003180291,0.0005362118,0.0006269136,0.0002854583,0.03601635],"genre_scores_gemma":[0.9962143,0.0006955313,0.0005701319,0.0005996777,0.0001245324,0.00002965568,0.0003697267,0.00001435385,0.001382024],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003215575,"threshold_uncertainty_score":0.006393731,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02182169100299321,"score_gpt":0.2640286123495386,"score_spread":0.2422069213465454,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}