{"id":"W2170204886","doi":"10.1186/1475-2867-7-17","title":"In vitro characterization and inhibition of the CXCR4/CXCL12 chemokine axis in human uveal melanoma cell lines","year":2007,"lang":"en","type":"article","venue":"Cancer Cell International","topic":"Chemokine receptors and signaling","field":"Medicine","cited_by":14,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University Health Centre","funders":"","keywords":"CXCR4; Chemokine receptor; Chemokine; Cell culture; Cell growth; Flow cytometry; Cell biology; Receptor; In vitro; Cell migration; Cell; Cancer research; Chemistry; Biology; Molecular biology; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003424849,0.000288412,0.0003751372,0.0002346405,0.000237582,0.0003471384,0.0001916991,0.000259517,0.001730498],"category_scores_gemma":[0.0001890798,0.0001380153,0.0003416038,0.0003728514,0.0001278271,0.0001264906,0.0001404194,0.0005076218,0.0007022624],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002558878,"about_ca_system_score_gemma":0.0002732318,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002910008,"about_ca_topic_score_gemma":0.003770855,"domain_scores_codex":[0.9996101,0.00008684811,0.00005503077,0.00004180862,0.0001365135,0.00006962952],"domain_scores_gemma":[0.9998349,0.00004054565,0.00002542456,0.00003129201,0.00005107182,0.00001684347],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001390683,0.0001380345,0.0008770366,0.0001398254,0.00001258276,0.00009875934,0.00007332595,0.0002098076,0.9950889,0.0000992897,0.0002015167,0.00292202],"study_design_scores_gemma":[0.00004897726,0.002505234,0.01145832,0.00002258167,0.00006125446,0.0007585573,0.0001062988,0.002321568,0.9744326,0.00002769404,0.008247285,0.000009533427],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9815469,0.005627568,0.006726764,0.0001524454,0.00008612801,0.0001950265,0.001442062,0.00007432783,0.004148771],"genre_scores_gemma":[0.9667323,0.004871061,0.01611297,0.0001292052,0.00004342742,0.0004268281,0.004827642,0.00002638054,0.006830109],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002910008,"threshold_uncertainty_score":0.005789101,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01010222042253964,"score_gpt":0.2691214444384004,"score_spread":0.2590192240158607,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}