{"id":"W2170310316","doi":"10.1038/msb.2013.23","title":"A global S. cerevisiae small ubiquitin‐related modifier (SUMO) system interactome","year":2013,"lang":"en","type":"article","venue":"Molecular Systems Biology","topic":"Ubiquitin and proteasome pathways","field":"Biochemistry, Genetics and Molecular Biology","cited_by":48,"is_retracted":false,"has_abstract":true,"ca_institutions":"University Health Network; University of Toronto; Ontario Institute for Cancer Research","funders":"Canadian Institutes of Health Research","keywords":"Interactome; Biology; Nucleoporin; Computational biology; Saccharomyces cerevisiae; Budding yeast; Ubiquitin; Tandem affinity purification; Ribosomal protein; SUMO protein; Proteases; Ubiquitin-Protein Ligases; Protein–protein interaction; Proteomics; Yeast; Biochemistry; Ubiquitin ligase; Ribosome; Affinity chromatography; Nuclear protein; Enzyme; RNA; Transcription factor; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001878705,0.00072852,0.0004411045,0.001101571,0.0004878729,0.0007892835,0.0001950925,0.0002336595,0.001986078],"category_scores_gemma":[0.0002294688,0.0002184588,0.000327692,0.001011024,0.0001728598,0.000473424,0.0006143955,0.0004072855,0.001020498],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004337907,"about_ca_system_score_gemma":0.0004649081,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0009304996,"about_ca_topic_score_gemma":0.002050167,"domain_scores_codex":[0.9998659,0.000009653915,0.00001004573,0.00005304821,0.00004069679,0.0000207775],"domain_scores_gemma":[0.9998381,0.00001658238,0.00002933925,0.00002444178,0.00003452008,0.00005697785],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0005546068,0.00004932904,0.01334757,0.0002980087,0.0001783086,0.0007880063,0.0001526555,0.0007400397,0.9483827,0.001799651,0.005149389,0.02855977],"study_design_scores_gemma":[0.0000643039,0.0002261452,0.1842389,0.00009288525,0.0004811914,0.004071886,0.0003532215,0.007969647,0.6929861,0.003117605,0.1063072,0.00009095595],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9103196,0.005666005,0.02924136,0.0006055915,0.0001066847,0.000100799,0.03993064,0.00386409,0.01016526],"genre_scores_gemma":[0.9105321,0.003132056,0.02630849,0.0002960789,0.00004664671,0.0001133936,0.05234567,0.0004496672,0.006775969],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001986078,"threshold_uncertainty_score":0.00664413,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.009979955803157041,"score_gpt":0.2339039462250495,"score_spread":0.2239239904218925,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}