{"id":"W2170310316","doi":"10.1038/msb.2013.23","title":"A global S. cerevisiae small ubiquitin‐related modifier (SUMO) system interactome","year":2013,"lang":"en","type":"article","venue":"Molecular Systems Biology","topic":"Ubiquitin and proteasome pathways","field":"Biochemistry, Genetics and Molecular Biology","cited_by":48,"is_retracted":false,"has_abstract":true,"ca_institutions":"University Health Network; University of Toronto; Ontario Institute for Cancer Research","funders":"Canadian Institutes of Health Research","keywords":"Interactome; Biology; Nucleoporin; Computational biology; Saccharomyces cerevisiae; Budding yeast; Ubiquitin; Tandem affinity purification; Ribosomal protein; SUMO protein; Proteases; Ubiquitin-Protein Ligases; Protein–protein interaction; Proteomics; Yeast; Biochemistry; Ubiquitin ligase; Ribosome; Affinity chromatography; Nuclear protein; Enzyme; RNA; Transcription factor; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0003726587,0.0004705612,0.0005478715,0.00009220733,0.0001121618,0.0001135534,0.0005915232,0.0007153531,0.00008755515],"category_scores_gemma":[0.00009649694,0.0004213878,0.0002816844,0.0002384835,0.0001447218,0.000007842609,0.0003348102,0.0001926231,0.0006683132],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001024925,"about_ca_system_score_gemma":0.00009841554,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007442777,"about_ca_topic_score_gemma":0.00001544294,"domain_scores_codex":[0.996847,0.0006210704,0.0007298602,0.0008879597,0.0001439018,0.0007701766],"domain_scores_gemma":[0.9982803,0.00001809709,0.0002931521,0.000874256,0.0002619949,0.0002721347],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00005730489,0.0000913634,0.00542303,0.0003543205,0.0004540765,0.00007259757,0.00006134322,0.0001413644,0.9649749,0.02267558,0.001566001,0.004128166],"study_design_scores_gemma":[0.01121406,0.006159781,0.01030152,0.001715523,0.0005382215,0.007326069,0.00258222,0.01415849,0.6491437,0.002354594,0.2867734,0.007732367],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9577539,0.005807959,0.01296181,0.0001400762,0.001204757,0.001465519,0.0001246756,0.0001650063,0.02037631],"genre_scores_gemma":[0.9974348,0.00003171607,0.0002695701,0.0003065211,0.0002676204,0.0004694178,0.0004265131,0.00005889414,0.0007349552],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.3158312,"threshold_uncertainty_score":0.9998238,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.009979955803157041,"score_gpt":0.2339039462250495,"score_spread":0.2239239904218925,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}