{"id":"W2170323717","doi":"10.1186/1477-5956-6-23","title":"The identification of disease-induced biomarkers in the urine of BSE infected cattle","year":2008,"lang":"en","type":"article","venue":"Proteome Science","topic":"Prion Diseases and Protein Misfolding","field":"Biochemistry, Genetics and Molecular Biology","cited_by":33,"is_retracted":false,"has_abstract":true,"ca_institutions":"Canadian Food Inspection Agency; University of Manitoba; Public Health Agency of Canada","funders":"Alberta Prion Research Institute; Public Health Agency; Public Health Agency of Canada","keywords":"Bovine spongiform encephalopathy; Urine; Disease; Medicine; Prion protein; Pathology; Biology; Internal medicine","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004135435,0.000325353,0.000290537,0.001204359,0.0003209145,0.0007303496,0.0001294085,0.0005005627,0.000391186],"category_scores_gemma":[0.0006802661,0.00010645,0.0001769078,0.0006599444,0.0003979025,0.0002200984,0.0002137573,0.0002809833,0.0001658355],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001919464,"about_ca_system_score_gemma":0.0001713438,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007265852,"about_ca_topic_score_gemma":0.000712204,"domain_scores_codex":[0.9997836,0.00003534351,0.00001706304,0.00004936333,0.0000739414,0.00004075002],"domain_scores_gemma":[0.99967,0.00008224684,0.00008633018,0.000009338849,0.0001085639,0.00004355102],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0006060618,0.0001238633,0.0706471,0.0002069983,0.00007384174,0.0002920557,0.0002221092,0.0001800741,0.9172385,0.00006761112,0.0001380511,0.01020385],"study_design_scores_gemma":[0.00001681487,0.0009781852,0.6412041,0.00006415979,0.0001615653,0.002864023,0.0006923131,0.00296205,0.3489121,0.0002423336,0.001874213,0.00002807423],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9952458,0.001631513,0.001958766,0.00006105372,0.00002494807,0.00001498855,0.0006557233,0.00003382266,0.0003733127],"genre_scores_gemma":[0.9937224,0.001044119,0.003722535,0.00008554957,0.00001906646,0.00002039158,0.0009234589,0.000007284561,0.0004550863],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001204359,"threshold_uncertainty_score":0.002187014,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01529718773579411,"score_gpt":0.2709969612208769,"score_spread":0.2556997734850828,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}