{"id":"W2170357921","doi":"10.2337/diabetes.54.9.2744","title":"Transgenic Mouse Overexpressing Syntaxin-1A as a Diabetes Model","year":2005,"lang":"en","type":"article","venue":"Diabetes","topic":"Pancreatic function and diabetes","field":"Medicine","cited_by":61,"is_retracted":false,"has_abstract":true,"ca_institutions":"Hospital for Sick Children; University of Toronto","funders":"Canadian Institutes of Health Research; Canadian Diabetes Association","keywords":"Exocytosis; Internal medicine; Endocrinology; Depolarization; Genetically modified mouse; Biology; Beta cell; Islet; Insulin; Glucose homeostasis; Cell biology; Diabetes mellitus; Secretion; Transgene; Insulin resistance; Biochemistry; Medicine","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003021671,0.001107421,0.0005724634,0.001450009,0.0004705175,0.0005923395,0.0006369581,0.001364831,0.003932517],"category_scores_gemma":[0.0002008718,0.0004635478,0.0005684437,0.0008353692,0.0005762356,0.0006109384,0.0004503289,0.002064986,0.001234289],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005183351,"about_ca_system_score_gemma":0.0002861166,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004075753,"about_ca_topic_score_gemma":0.0005550613,"domain_scores_codex":[0.999622,0.00003613219,0.00004735873,0.0001673132,0.00007410656,0.00005310825],"domain_scores_gemma":[0.9996507,0.0000465698,0.0001246073,0.0000352887,0.00003096684,0.0001118161],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0005238808,0.0004169501,0.0005600798,0.00007547482,0.0000312638,0.0008616693,0.00006172113,0.0001074955,0.9933297,0.0008798821,0.0004200208,0.00273185],"study_design_scores_gemma":[0.001065539,0.006659264,0.02344597,0.0001781877,0.0005491797,0.01818339,0.000310399,0.006237422,0.8907878,0.001969575,0.05048955,0.000123761],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9731798,0.002499717,0.01270243,0.0009192341,0.000449221,0.0004152219,0.004439889,0.001156633,0.004237877],"genre_scores_gemma":[0.9475217,0.005125606,0.01697256,0.0007436706,0.0001569102,0.001015804,0.00639981,0.0003029534,0.021761],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003932517,"threshold_uncertainty_score":0.01315552,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01613694527626531,"score_gpt":0.2521908823541403,"score_spread":0.236053937077875,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}