{"id":"W2170385470","doi":"10.1139/v05-144","title":"Hydrolysis of aryl hydrogen maleate esters mediated by cyclodextrins Effect on the intramolecular catalysis","year":2005,"lang":"en","type":"article","venue":"Canadian Journal of Chemistry","topic":"Drug Solubulity and Delivery Systems","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":5,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Consejo Nacional de Investigaciones Científicas y Técnicas; Agencia Córdoba Ciencia","keywords":"Chemistry; Reaction rate constant; Intramolecular force; Substituent; Catalysis; Medicinal chemistry; Aryl; Hydrolysis; Substrate (aquarium); Carboxylate; Maleic anhydride; Stereochemistry; Kinetics; Organic chemistry","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":true,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003347349,0.0004782809,0.0004218601,0.0001250833,0.00007718319,0.0003483499,0.0002538767,0.000283813,0.0009489887],"category_scores_gemma":[0.0004027512,0.0001953645,0.0003384858,0.0001535027,0.0002495559,0.0003437097,0.0002761998,0.0004875977,0.0003431905],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001849388,"about_ca_system_score_gemma":0.000169634,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002445569,"about_ca_topic_score_gemma":0.0002313348,"domain_scores_codex":[0.9997314,0.00006113694,0.00002754551,0.0000446827,0.0000651119,0.0000701527],"domain_scores_gemma":[0.9997687,0.00008686951,0.00005660777,0.00002252514,0.00003128421,0.00003409257],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001668755,0.00002887572,0.0001427935,0.00007265402,0.0000128576,0.00004891078,0.00002023541,0.0002184314,0.9976848,0.00008864845,0.00001554077,0.001499393],"study_design_scores_gemma":[0.000003728353,0.00008657896,0.0005388292,0.000003751601,0.000005384519,0.00003055642,0.000007211896,0.000446401,0.9986394,0.00001051709,0.0002240301,0.000003606465],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9962191,0.0006925439,0.001636924,0.00002766537,0.00001500425,0.00002264365,0.00006127152,0.00002529365,0.001299555],"genre_scores_gemma":[0.9973539,0.0006026325,0.0009378407,0.00001779504,0.000004650489,0.00001776611,0.00008352329,0.000009662319,0.0009721447],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0009489887,"threshold_uncertainty_score":0.003174722,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02175750359903777,"score_gpt":0.2968627784076158,"score_spread":0.275105274808578,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}