{"id":"W2170428123","doi":"10.1111/j.1365-2133.2009.09209.x","title":"Adapalene-benzoyl peroxide, a unique fixed-dose combination topical gel for the treatment of acne vulgaris: a transatlantic, randomized, double-blind, controlled study in 1670 patients","year":2009,"lang":"en","type":"article","venue":"British Journal of Dermatology","topic":"Acne and Rosacea Treatments and Effects","field":"Medicine","cited_by":128,"is_retracted":false,"has_abstract":true,"ca_institutions":"Innovation Initiatives Ontario North","funders":"","keywords":"Adapalene; Acne; Benzoyl peroxide; Dermatology; Medicine; Double blind; Randomized controlled trial; Internal medicine; Chemistry; Pathology; Organic chemistry; Placebo","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002768159,0.0001694545,0.00154875,0.0001457953,0.00008177456,0.00002112551,0.00009044244,0.0001343041,0.00001962841],"category_scores_gemma":[0.00008991777,0.0001049257,0.0004293629,0.00009782887,0.00007110555,0.00007785221,0.000004474097,0.0001501259,8.616257e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00006135272,"about_ca_system_score_gemma":0.0000983355,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001155959,"about_ca_topic_score_gemma":0.0001560182,"domain_scores_codex":[0.9981785,0.0002975167,0.0009480864,0.0001403795,0.0002096731,0.0002258692],"domain_scores_gemma":[0.9985355,0.0006224852,0.0003819342,0.0001146991,0.0002580343,0.00008738102],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.8725795,0.02879814,0.04218811,0.00007218647,0.002062875,0.002682733,0.0024851,0.0000188099,0.00009174369,0.0002448242,0.000704301,0.04807167],"study_design_scores_gemma":[0.9416891,0.006445745,0.04592805,0.0001894445,0.0012936,0.002944809,0.0003154768,0.0002897658,0.0004859834,0.0001085723,0.0002155694,0.00009386666],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9884694,0.003763777,0.0005240311,0.002709972,0.0001536873,0.004299341,0.000005261671,0.000005488989,0.00006908141],"genre_scores_gemma":[0.9970499,0.002388872,0.0001227567,0.000165,0.00005463589,0.0001125904,0.00001301588,0.000009940103,0.00008326182],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0691096,"threshold_uncertainty_score":0.4278744,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02047782899228674,"score_gpt":0.3020965266291488,"score_spread":0.2816186976368621,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}