{"id":"W2170428123","doi":"10.1111/j.1365-2133.2009.09209.x","title":"Adapalene-benzoyl peroxide, a unique fixed-dose combination topical gel for the treatment of acne vulgaris: a transatlantic, randomized, double-blind, controlled study in 1670 patients","year":2009,"lang":"en","type":"article","venue":"British Journal of Dermatology","topic":"Acne and Rosacea Treatments and Effects","field":"Medicine","cited_by":128,"is_retracted":false,"has_abstract":true,"ca_institutions":"Innovation Initiatives Ontario North","funders":"","keywords":"Adapalene; Acne; Benzoyl peroxide; Dermatology; Medicine; Double blind; Randomized controlled trial; Internal medicine; Chemistry; Pathology; Organic chemistry; Placebo","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.002250815,0.0012603,0.003870203,0.0005813349,0.0004634833,0.0006808135,0.0005964021,0.001221831,0.004591106],"category_scores_gemma":[0.001191383,0.0007991365,0.001323311,0.000589515,0.001259382,0.0007680173,0.0003506727,0.001620692,0.0006491439],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005016109,"about_ca_system_score_gemma":0.001147485,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0008726054,"about_ca_topic_score_gemma":0.001648302,"domain_scores_codex":[0.999188,0.0003629777,0.00007012112,0.0001784978,0.00008877515,0.000111564],"domain_scores_gemma":[0.9991209,0.0002625606,0.0001720156,0.00005718349,0.00008183816,0.0003055726],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.9330807,0.02392493,0.003280967,0.001626425,0.001068266,0.00008878417,0.0001279101,0.000213757,0.009438841,0.00008081371,0.0007328857,0.02633579],"study_design_scores_gemma":[0.7559506,0.2357488,0.006080011,0.00003805263,0.0006977954,0.00005776434,0.00003943956,0.000224564,0.0005062037,0.00003421768,0.0006067704,0.00001586046],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9864668,0.007893491,0.0005650802,0.0001619896,0.0002782867,0.003403177,0.000458326,0.0000610247,0.0007118128],"genre_scores_gemma":[0.9863456,0.004367818,0.001869181,0.000595753,0.0005274219,0.004474841,0.0004780798,0.0000164373,0.001324742],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.004591106,"threshold_uncertainty_score":0.01535881,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02047782899228674,"score_gpt":0.3020965266291488,"score_spread":0.2816186976368621,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}