{"id":"W2170538199","doi":"10.1186/gb-2012-13-2-r8","title":"Population-specificity of human DNA methylation","year":2012,"lang":"en","type":"article","venue":"Genome biology","topic":"Epigenetics and DNA Methylation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":325,"is_retracted":false,"has_abstract":true,"ca_institutions":"Child and Family Research Institute; University of British Columbia","funders":"National Human Genome Research Institute; National Institute of Mental Health; National Institutes of Health; Canadian Institute for Advanced Research","keywords":"Biology; Human genetics; Genome Biology; DNA methylation; Genetics; Evolutionary biology; Computational biology; Population; DNA; Methylation; Human genome; Genomics; Genome; Gene; Gene expression","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003201202,0.00009568128,0.0001402172,0.00005691177,0.00006046612,0.00000317809,0.00009350497,0.0001782819,0.00006483406],"category_scores_gemma":[0.00003820933,0.00009220094,0.00006361451,0.00006921445,0.00004991219,0.000003214027,0.00005574389,0.00004000079,0.000009975421],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001181822,"about_ca_system_score_gemma":0.00000875407,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00004089574,"about_ca_topic_score_gemma":0.00001417671,"domain_scores_codex":[0.9992256,0.0001006252,0.0002488086,0.0001694111,0.00004954219,0.0002060181],"domain_scores_gemma":[0.9994913,0.00001135194,0.000137716,0.0002391038,0.00006241492,0.00005815757],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.000008771073,0.0000336113,0.1152967,0.000004787486,0.00001682275,2.005032e-8,0.00003419694,0.00001275467,0.881055,0.002026665,0.00000720377,0.001503407],"study_design_scores_gemma":[0.0001570007,0.0001789996,0.4961304,0.000001015757,0.000009959517,4.690929e-7,0.0000138952,0.000002120628,0.4867781,0.001025279,0.0155853,0.0001174724],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9919327,0.003109997,0.002864501,0.00001686,0.0001852389,0.0001048617,0.00002120183,0.000007296273,0.001757311],"genre_scores_gemma":[0.997766,0.0001181067,0.0006816612,0.00002064543,0.0004663778,0.000006776903,0.0008194781,0.00001208024,0.0001089439],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.3942769,"threshold_uncertainty_score":0.3759845,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02569254122304624,"score_gpt":0.2989568044224803,"score_spread":0.2732642631994341,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}