{"id":"W2170569802","doi":"10.1002/wnan.95","title":"Blood replacement with nanobiotechnologically engineered hemoglobin and hemoglobin nanocapsules","year":2010,"lang":"en","type":"review","venue":"Wiley Interdisciplinary Reviews Nanomedicine and Nanobiotechnology","topic":"Hemoglobin structure and function","field":"Biochemistry, Genetics and Molecular Biology","cited_by":59,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University","funders":"Canadian Institutes of Health Research; Health Canada; Medical Research Council Canada","keywords":"Blood substitute; Hemoglobin; Chemistry; Nanocapsules; Polylactic acid; Polyethylene glycol; Polymer; Biochemistry; Nanoparticle; Nanotechnology; Materials science; Organic chemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001554616,0.0001972426,0.0001523373,0.0002117458,0.0000663698,0.0001928691,0.0001946293,0.0003127676,0.0004086478],"category_scores_gemma":[0.0001333457,0.000100516,0.0002307151,0.0001210369,0.0001466807,0.0002075419,0.0001523953,0.000238524,0.0001987493],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000281057,"about_ca_system_score_gemma":0.0001609721,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002646718,"about_ca_topic_score_gemma":0.000342691,"domain_scores_codex":[0.9999037,0.00001307037,0.000008516242,0.00002429112,0.00004175682,0.00000875071],"domain_scores_gemma":[0.9999415,0.00001147623,0.0000234572,0.000006066347,0.00001042821,0.000007113128],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0000969634,0.00007785746,0.0002252857,0.0002101304,0.00002182624,0.0001244434,0.00002365108,0.0009796936,0.9762033,0.0009296576,0.0004974775,0.02060961],"study_design_scores_gemma":[0.00005975884,0.0005285307,0.001109895,0.00002435137,0.00004888196,0.0006420369,0.00001385301,0.006435572,0.9743115,0.000367977,0.01643921,0.00001835847],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"review","genre_scores_codex":[0.791771,0.04619611,0.1528684,0.0007864304,0.001373251,0.0002604061,0.0002819254,0.0006259807,0.005836502],"genre_scores_gemma":[0.8876203,0.01115878,0.09198458,0.0005809666,0.0002045126,0.0002623586,0.0002620485,0.00006580763,0.007860633],"genre_candidate":"review","genre_consensus":null,"teacher_disagreement_score":0.0004086478,"threshold_uncertainty_score":0.002039194,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01142127462500594,"score_gpt":0.2770889332945964,"score_spread":0.2656676586695905,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}