{"id":"W2170627452","doi":"10.1158/1940-6207.capr-08-0209","title":"The Chemopreventive Agent Myoinositol Inhibits Akt and Extracellular Signal-Regulated Kinase in Bronchial Lesions from Heavy Smokers","year":2009,"lang":"en","type":"article","venue":"Cancer Prevention Research","topic":"Genomics, phytochemicals, and oxidative stress","field":"Biochemistry, Genetics and Molecular Biology","cited_by":53,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia; BC Cancer Agency","funders":"National Cancer Institute; National Institutes of Health","keywords":"Protein kinase B; Kinase; Extracellular; Medicine; Phosphorylation; Pharmacology; Cancer research; Chemistry; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002319833,0.0002547517,0.0004225373,0.0004077338,0.0001934043,0.0001727066,0.0001391016,0.0003172298,0.0009410904],"category_scores_gemma":[0.000190139,0.0002413085,0.0003173741,0.0001800229,0.0001570455,0.00009216968,0.0001984109,0.0004538471,0.0002488728],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001273143,"about_ca_system_score_gemma":0.000169063,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007837255,"about_ca_topic_score_gemma":0.001680274,"domain_scores_codex":[0.9998925,0.00002552505,0.000008711701,0.00001407056,0.00002634728,0.00003287937],"domain_scores_gemma":[0.9999169,0.00001581861,0.00001721058,0.000009098794,0.000007967391,0.00003295608],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.002580647,0.0003450106,0.006159082,0.00007092636,0.00003526755,0.0001363056,0.00003655289,0.00004366381,0.9783146,0.00002047621,0.00008415119,0.01217345],"study_design_scores_gemma":[0.0007913854,0.01873315,0.3503492,0.00003414052,0.0002642558,0.001951943,0.0001443673,0.001614939,0.6213247,0.0001291961,0.00464741,0.00001535131],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9972605,0.001954114,0.0002112271,0.00004751466,0.0000117706,0.00003149907,0.00004808695,0.00001770098,0.0004175827],"genre_scores_gemma":[0.9966191,0.001546935,0.0004013537,0.00007715263,0.00001898228,0.0000312185,0.000262967,0.000008312696,0.001033887],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0009410904,"threshold_uncertainty_score":0.003148258,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03756945024443171,"score_gpt":0.3551634735227345,"score_spread":0.3175940232783028,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}